Molecular mechanisms of action of epigallocatechin gallate in cancer: Recent trends and advancement

V Aggarwal, HS Tuli, M Tania, S Srivastava… - Seminars in cancer …, 2022 - Elsevier
Epigallocatechin gallate (EGCG), also known as epigallocatechin-3-gallate, is an ester of
epigallocatechin and gallic acid. EGCG, abundantly found in tea, is a polyphenolic flavonoid …

Phytochemicals as chemo-preventive agents and signaling molecule modulators: current role in cancer therapeutics and inflammation

MB Ahmed, SU Islam, AAA Alghamdi… - International Journal of …, 2022 - mdpi.com
Cancer is one of the deadliest non communicable diseases. Numerous anticancer
medications have been developed to target the molecular pathways driving cancer …

[HTML][HTML] Herbal drugs and natural bioactive products as potential therapeutics: A review on pro-cognitives and brain boosters perspectives

S Halder, U Anand, S Nandy, P Oleksak, S Qusti… - Saudi Pharmaceutical …, 2021 - Elsevier
Memory, one of the most vital aspects of the human brain, is necessary for the effective
survival of an individual.'Memory'can be defined in various ways but in an overall view …

Therapeutic influence on important targets associated with chronic inflammation and oxidative stress in cancer treatment

M Neganova, J Liu, Y Aleksandrova, S Klochkov, R Fan - Cancers, 2021 - mdpi.com
Simple Summary There is no doubt that the need for new effective methods of cancer
treatment remains challenging, as cancer is the second cause of death based on the …

Rational selection of bioactive principles for wound healing applications: Growth factors and antioxidants

P Viaña‐Mendieta, ML Sánchez… - International wound …, 2022 - Wiley Online Library
Wound healing is a complex process of communication between growth factors, reactive
species of oxygen, cells, signalling pathways, and cytokines in the extracellular matrix, in …

[HTML][HTML] EGCG inhibits tumor growth in melanoma by targeting JAK-STAT signaling and its downstream PD-L1/PD-L2-PD1 axis in tumors and enhancing cytotoxic T …

DR Menon, Y Li, T Yamauchi, DG Osborne… - …, 2021 - ncbi.nlm.nih.gov
Over the last decade, therapies targeting immune checkpoints, such as programmed death-
1 (PD-1), have revolutionized the field of cancer immunotherapy. However, low response …

Bilosomes as effective delivery systems to improve the gastrointestinal stability and bioavailability of epigallocatechin gallate (EGCG)

L Wang, X Huang, H Jing, C Ma, H Wang - Food research international, 2021 - Elsevier
Epigallocatechin gallate (EGCG) has a variety of biological activities, but exhibits poor
stability and low bioavailability. In this study, EGCG bilosome was prepared and …

Protective effects of epigallocatechin gallate (EGCG) on endometrial, breast, and ovarian cancers

YJ Huang, KL Wang, HY Chen, YF Chiang, SM Hsia - Biomolecules, 2020 - mdpi.com
Green tea and its major bioactive component,(−)-epigallocatechin gallate (EGCG), possess
diverse biological properties, particularly antiproliferation, antimetastasis, and apoptosis …

Natural plant resource flavonoids as potential therapeutic drugs for pulmonary fibrosis

MC Wang - Heliyon, 2023 - cell.com
Pulmonary fibrosis is an enduring and advancing pulmonary interstitial disease caused by
multiple factors that ultimately lead to structural changes in normal lung tissue. Currently …

Egcg inhibits tumor growth in melanoma by targeting jak-stat signaling and its downstream Pd-L1/Pd-L2-Pd1 axis in tumors and enhancing cytotoxic T-cell responses

D Ravindran Menon, Y Li, T Yamauchi, DG Osborne… - Pharmaceuticals, 2021 - mdpi.com
Over the last decade, therapies targeting immune checkpoints, such as programmed death-
1 (PD-1), have revolutionized the field of cancer immunotherapy. However, low response …