Human T-cell leukaemia virus type I and adult T-cell leukaemia-lymphoma

K Ishitsuka, K Tamura - The Lancet Oncology, 2014 - thelancet.com
Adult T-cell leukaemia-lymphoma (ATL) is a malignancy of peripheral T lymphocytes caused
by human T-lymphotropic virus type I (HTLV-1), and its prognosis is poor. There are an …

Adult T-cell leukemia: a review of epidemiological evidence

M Iwanaga, T Watanabe, K Yamaguchi - Frontiers in microbiology, 2012 - frontiersin.org
Adult T-cell leukemia (ATL) is an aggressive T-cell malignancy caused by human T-cell
leukemia virus type I (HTLV-1) infection and often occurs in HTLV-1-endemic areas, such as …

Revised adult T-cell leukemia-lymphoma international consensus meeting report

LB Cook, S Fuji, O Hermine, A Bazarbachi… - Journal of Clinical …, 2019 - ascopubs.org
Purpose Adult T-cell leukemia-lymphoma (ATL) is a distinct mature T-cell malignancy
caused by chronic infection with human T-lymphotropic virus type 1 with diverse clinical …

Human T-cell leukemia virus type I (HTLV-1) proviral load and disease progression in asymptomatic HTLV-1 carriers: a nationwide prospective study in Japan

M Iwanaga, T Watanabe, A Utsunomiya… - Blood, The Journal …, 2010 - ashpublications.org
Definitive risk factors for the development of adult T-cell leukemia (ATL) among
asymptomatic human T-cell leukemia virus type I (HTLV-1) carriers remain unclear …

HTLV-1 infection and adult T-cell leukemia/lymphoma—a tale of two proteins: tax and HBZ

CZ Giam, OJ Semmes - Viruses, 2016 - mdpi.com
HTLV-1 (Human T-cell lymphotropic virus type 1) is a complex human delta retrovirus that
currently infects 10–20 million people worldwide. While HTLV-1 infection is generally …

Natural history of adult T-cell leukemia/lymphoma and approaches to therapy

GP Taylor, M Matsuoka - Oncogene, 2005 - nature.com
After cell-to-cell transmission, HTLV-I increases its viral genome by de novo infection and
proliferation of infected cells. Proliferation of infected cells is clonal and persistent in vivo …

[HTML][HTML] 40 years of the human T-cell leukemia virus: past, present, and future

Y Tagaya, M Matsuoka, R Gallo - F1000Research, 2019 - ncbi.nlm.nih.gov
It has been nearly 40 years since human T-cell leukemia virus-1 (HTLV-1), the first
oncogenic retrovirus in humans and the first demonstrable cause of cancer by an infectious …

Human T-cell leukemia virus type I (HTLV-I) infection and the onset of adult T-cell leukemia (ATL)

M Matsuoka - Retrovirology, 2005 - Springer
The clinical entity of adult T-cell leukemia (ATL) was established around 1977, and human T-
cell leukemia virus type 1 (HTLV-I) was subsequently identified in 1980. In the 25 years …

Precise excision of HTLV-1 provirus with a designer-recombinase

T Rojo-Romanos, J Karpinski, S Millen, N Beschorner… - Molecular Therapy, 2023 - cell.com
The human T cell leukemia virus type 1 (HTLV-1) is a pathogenic retrovirus that persists as a
provirus in the genome of infected cells and can lead to adult T cell leukemia (ATL) …

Abnormally High Levels of Virus-Infected IFN-γ+CCR4+CD4+CD25+ T Cells in a Retrovirus-Associated Neuroinflammatory Disorder

Y Yamano, N Araya, T Sato, A Utsunomiya, K Azakami… - PloS one, 2009 - journals.plos.org
Background Human T-lymphotropic virus type 1 (HTLV-1) is a human retrovirus associated
with both HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP), which is a …