Ketogenic diet for human diseases: the underlying mechanisms and potential for clinical implementations
The ketogenic diet (KD) is a high-fat, adequate-protein, and very-low-carbohydrate diet
regimen that mimics the metabolism of the fasting state to induce the production of ketone …
regimen that mimics the metabolism of the fasting state to induce the production of ketone …
β-hydroxybutyrate as an Anti-Aging Metabolite
L Wang, P Chen, W Xiao - Nutrients, 2021 - mdpi.com
The ketone bodies, especially β-hydroxybutyrate (β-HB), derive from fatty acid oxidation and
alternatively serve as a fuel source for peripheral tissues including the brain, heart, and …
alternatively serve as a fuel source for peripheral tissues including the brain, heart, and …
Nutrients to improve mitochondrial function to reduce brain energy deficit and oxidative stress in migraine
M Fila, C Chojnacki, J Chojnacki, J Blasiak - Nutrients, 2021 - mdpi.com
The mechanisms of migraine pathogenesis are not completely clear, but 31P-nuclear
magnetic resonance studies revealed brain energy deficit in migraineurs. As glycolysis is the …
magnetic resonance studies revealed brain energy deficit in migraineurs. As glycolysis is the …
Ketone bodies and SIRT1, synergic epigenetic regulators for metabolic health: a narrative review
R Tozzi, F Cipriani, D Masi, S Basciani, M Watanabe… - Nutrients, 2022 - mdpi.com
Ketone bodies (KBs) and Sirtuin-1 (SIRT1) have received increasing attention over the past
two decades given their pivotal function in a variety of biological contexts, including …
two decades given their pivotal function in a variety of biological contexts, including …
Ketone body β-hydroxybutyric acid ameliorates dopaminergic neuron injury through modulating zinc finger protein 36/Acyl-CoA synthetase long-chain family member …
X Yu, Y Yang, B Zhang, G Han, J Yu, Q Yu, L Zhang - Neuroscience, 2023 - Elsevier
Abstract β-hydroxybutyrate (BHB) is one of main component of ketone body, which plays an
important protective role in various tissues and organs. Whereas, its exact regulatory roles …
important protective role in various tissues and organs. Whereas, its exact regulatory roles …
[HTML][HTML] Improving the effectiveness of anti-aging modalities by using the constrained disorder principle-based management algorithms
N Hurvitz, N Elkhateeb, T Sigawi, L Rinsky-Halivni… - Frontiers in …, 2022 - frontiersin.org
Aging is a complex biological process with multifactorial nature underlined by genetic,
environmental, and social factors. In the present paper, we review several mechanisms of …
environmental, and social factors. In the present paper, we review several mechanisms of …
Multiple metabolites derived from mushrooms and their beneficial effect on Alzheimer's diseases
Z Tong, G Chu, C Wan, Q Wang, J Yang, Z Meng, L Du… - Nutrients, 2023 - mdpi.com
Mushrooms with edible and medicinal potential have received widespread attention
because of their diverse biological functions, nutritional value, and delicious taste, which are …
because of their diverse biological functions, nutritional value, and delicious taste, which are …
Ketogenic diet ameliorates autism spectrum disorders-like behaviors via reduced inflammatory factors and microbiota remodeling in BTBR T+ Itpr3tf/J mice
Abstract Autism Spectrum Disorder (ASD) is increasing, but its complete etiology is still
lacking. Recently, application of ketogenic diet (KD) has shown to reduce abnormal …
lacking. Recently, application of ketogenic diet (KD) has shown to reduce abnormal …
Role of diet in stem and cancer stem cells
F Puca, M Fedele, D Rasio, S Battista - International journal of molecular …, 2022 - mdpi.com
Diet and lifestyle factors greatly affect health and susceptibility to diseases, including cancer.
Stem cells' functions, including their ability to divide asymmetrically, set the rules for tissue …
Stem cells' functions, including their ability to divide asymmetrically, set the rules for tissue …
[HTML][HTML] Targeting macroautophagy as a therapeutic opportunity to treat parkinson's disease
I Sanchez-Mirasierra, S Ghimire… - Frontiers in cell and …, 2022 - frontiersin.org
Macroautophagy, an evolutionary conserved catabolic process in the eukaryotic cell,
regulates cellular homeostasis and plays a decisive role in self-engulfing proteins, protein …
regulates cellular homeostasis and plays a decisive role in self-engulfing proteins, protein …