Bone morphogenetic protein-2 (BMP-2) is currently the only Food and Drug Administration
(FDA)-approved osteoinductive growth factor used as a bone graft substitute. However, with …

Bone morphogenetic proteins (BMPs) are responsible for bone formation during
embryogenesis and bone regeneration and remodeling. The osteoinductive action of BMPs …

Bone morphogenetic proteins (BMPs) are cytokines with a strong effect on bone and
cartilage growth and with important roles during embryonic patterning and early skeletal …

Non-healing fractures can result from trauma, disease, or age-related bone loss. While many
treatments focus on restoring bone volume, few try to recapitulate bone organization …

Localized and release-controlled delivery systems for the sustained expression of the
biologic potency of rhBMPs are essential. A substantial number of biomaterials have been …

Background: Reconstructive surgery of the head and neck is both technically challenging
and rewarding. In the past 20 years, significant advances in this field have improved surgical …

OBJECTIVE: In this study we evaluated the effects of sodium hyaluronate (HY) in the healing
process of tooth sockets of rats. DESIGN: Immediately after the extraction of the upper first …

Trauma and disease frequently result in fractures or critical sized bone defects and their
management at times necessitates bone grafting. The process of bone healing or …

The capacity to deliver, temporally, bioactive growth factors in combination with appropriate
progenitor and stem cells to sites of tissue regeneration promoting angiogenesis and …

Segmental defect regeneration has been a clinical challenge. Current tissue-engineering
approach using porous biodegradable scaffolds to delivery osteogenic cells and growth …