Exploitation of recombinant DNA and sequencing technologies has led to a new concept in
vaccination in which isolated epitopes, capable of stimulating a specific immune response …

Cancer immunotherapy is a method of controlling and eliminating tumors by reactivating the
body's cancer-immunity cycle and restoring its antitumor immune response. The increased …

Abstract At present, novel Coronavirus (2019-nCoV, the causative agent of COVID-19) has
caused worldwide social and economic disruption. The disturbing statistics of this infection …

Both microbial and host genetic factors contribute to the pathogenesis of autoimmune
diseases,,,. There is accumulating evidence that microbial species that potentiate chronic …

Computational prediction of T cell epitope candidates is currently being used in several
applications including vaccine discovery studies, development of diagnostics, and removal …

Prediction of HLA binding affinity is widely used to identify candidate T cell epitopes, and an
affinity of 500 nM is routinely used as a threshold for peptide selection. However, the fraction …

Staphylococcus aureus is a pathogen that causes a variety of infections in humans.
Methicillin-resistant S. aureus, which is an antibiotic-resistant form, is responsible for …

The lack of available vaccines against African swine fever virus (ASFV) means that the
evaluation of new immunization strategies is required. Here we show that fusion of the …

Ag presentation on HLA molecules plays a central role in infectious diseases and tumor
immunology. To date, large-scale identification of (neo-) Ags from DNA sequencing data has …

In recent decades, the development of plant virology and genetic engineering techniques
has resulted in the construction of plant virus-based vaccines for protection against different …