Regulation of Nuclear Factor-KappaB (NF-κB) signaling pathway by non-coding RNAs in cancer: Inhibiting or promoting carcinogenesis?
The nuclear factor-kappaB (NF-κB) signaling pathway is considered as a potential
therapeutic target in cancer therapy. It has been well established that transcription factor NF …
therapeutic target in cancer therapy. It has been well established that transcription factor NF …
[HTML][HTML] Progress of breast cancer basic research in China
X Wang, C Wang, J Guan, B Chen, L Xu… - International Journal of …, 2021 - ncbi.nlm.nih.gov
Breast cancer is the most commonly diagnosed and the most lethal cancer in females both
in China and worldwide. Currently, the origin of cancer stem cells, the heterogeneity of …
in China and worldwide. Currently, the origin of cancer stem cells, the heterogeneity of …
The FUS/circEZH2/KLF5/feedback loop contributes to CXCR4-induced liver metastasis of breast cancer by enhancing epithelial-mesenchymal transition
P Liu, Z Wang, X Ou, P Wu, Y Zhang, S Wu, X Xiao… - Molecular cancer, 2022 - Springer
Background Metastasis of breast cancer have caused the majority of cancer-related death
worldwide. The circRNAs are associated with tumorigenesis and metastasis in breast cancer …
worldwide. The circRNAs are associated with tumorigenesis and metastasis in breast cancer …
Lnc2Cancer 3.0: an updated resource for experimentally supported lncRNA/circRNA cancer associations and web tools based on RNA-seq and scRNA-seq data
Y Gao, S Shang, S Guo, X Li, H Zhou, H Liu… - Nucleic acids …, 2021 - academic.oup.com
Abstract An updated Lnc2Cancer 3.0 (http://www. bio-bigdata. net/lnc2cancer or http://bio-
bigdata. hrbmu. edu. cn/lnc2cancer) database, which includes comprehensive data on …
bigdata. hrbmu. edu. cn/lnc2cancer) database, which includes comprehensive data on …
CircIL4R activates the PI3K/AKT signaling pathway via the miR-761/TRIM29/PHLPP1 axis and promotes proliferation and metastasis in colorectal cancer
T Jiang, H Wang, L Liu, H Song, Y Zhang, J Wang… - Molecular Cancer, 2021 - Springer
Background Accumulating studies have revealed that aberrant expression of circular RNAs
(circRNAs) is widely involved in the tumorigenesis and progression of malignant cancers …
(circRNAs) is widely involved in the tumorigenesis and progression of malignant cancers …
[HTML][HTML] A novel axis of circKIF4A-miR-637-STAT3 promotes brain metastasis in triple-negative breast cancer
S Wu, J Lu, H Zhu, F Wu, Y Mo, L Xie, C Song, L Liu… - Cancer Letters, 2024 - Elsevier
Among patients with triple-negative breast cancer (TNBC), distant metastasis is the leading
cause of death. Our previous studies have shown that TNBC progression is greatly …
cause of death. Our previous studies have shown that TNBC progression is greatly …
[HTML][HTML] Circular RNA circRHOBTB3 represses metastasis by regulating the HuR-mediated mRNA stability of PTBP1 in colorectal cancer
J Chen, Y Wu, X Luo, D Jin, W Zhou, Z Ju, D Wang… - Theranostics, 2021 - ncbi.nlm.nih.gov
Background: Tumor metastasis of colorectal cancer (CRC) is the main cause of death in
most patients and the major difficulty in comprehensive CRC treatment. Circular RNAs …
most patients and the major difficulty in comprehensive CRC treatment. Circular RNAs …
EIF4A3-induced circARHGAP29 promotes aerobic glycolysis in docetaxel-resistant prostate cancer through IGF2BP2/c-Myc/LDHA signaling
X Jiang, S Guo, S Wang, Y Zhang, H Chen, Y Wang… - Cancer research, 2022 - AACR
Docetaxel-based chemotherapy is a standard-of-care treatment for metastatic prostate
cancer, and chemoresistance remains a major challenge in clinical practice. Recent studies …
cancer, and chemoresistance remains a major challenge in clinical practice. Recent studies …
[HTML][HTML] Circular RNA circPPM1F modulates M1 macrophage activation and pancreatic islet inflammation in type 1 diabetes mellitus
C Zhang, X Han, L Yang, J Fu, C Sun, S Huang… - Theranostics, 2020 - ncbi.nlm.nih.gov
Rationale: Macrophages play critical roles in the pathogenesis of type 1 diabetes mellitus
(T1DM). Circular RNAs (circRNAs) are a novel class of endogenous RNAs with covalently …
(T1DM). Circular RNAs (circRNAs) are a novel class of endogenous RNAs with covalently …
Diagnostic efficacy of circular RNAs as noninvasive, liquid biopsy biomarkers for early detection of gastric cancer
Background Majority of gastric cancers (GC) are diagnosed at advanced stages which
contributes towards their poor prognosis. In view of this clinical challenge, identification of …
contributes towards their poor prognosis. In view of this clinical challenge, identification of …