Immune response to SARS‐CoV‐2 and mechanisms of immunopathological changes in COVID‐19
As a zoonotic disease that has already spread globally to several million human beings and
possibly to domestic and wild animals, eradication of coronavirus disease 2019 (COVID‐19) …
possibly to domestic and wild animals, eradication of coronavirus disease 2019 (COVID‐19) …
Recent applications of immunomodulatory biomaterials for disease immunotherapy
Immunotherapy is used to regulate systemic hyperactivation or hypoactivation to treat
various diseases. Biomaterial‐based immunotherapy systems can improve therapeutic …
various diseases. Biomaterial‐based immunotherapy systems can improve therapeutic …
Type 2 immunity in the skin and lungs
CA Akdis, PD Arkwright, MC Brüggen, W Busse… - Allergy, 2020 - Wiley Online Library
There has been extensive progress in understanding the cellular and molecular
mechanisms of inflammation and immune regulation in allergic diseases of the skin and …
mechanisms of inflammation and immune regulation in allergic diseases of the skin and …
Immunosuppressive mechanisms of regulatory B cells
D Catalán, MA Mansilla, A Ferrier, L Soto… - Frontiers in …, 2021 - frontiersin.org
Regulatory B cells (Bregs) is a term that encompasses all B cells that act to suppress
immune responses. Bregs contribute to the maintenance of tolerance, limiting ongoing …
immune responses. Bregs contribute to the maintenance of tolerance, limiting ongoing …
Cellular and molecular mechanisms of allergic asthma
Asthma is a chronic disease of the airways, which affects more than 350 million people
worldwide. It is the most common chronic disease in children, affecting at least 30 million …
worldwide. It is the most common chronic disease in children, affecting at least 30 million …
[HTML][HTML] Mechanisms of allergen immunotherapy for inhaled allergens and predictive biomarkers
Allergen immunotherapy is effective in patients with IgE-dependent allergic rhinitis and
asthma. When immunotherapy is given continuously for 3 years, there is persistent clinical …
asthma. When immunotherapy is given continuously for 3 years, there is persistent clinical …
Type 2 chronic inflammatory diseases: targets, therapies and unmet needs
Over the past two decades, significant progress in understanding of the pathogenesis of type
2 chronic inflammatory diseases has enabled the identification of compounds for more than …
2 chronic inflammatory diseases has enabled the identification of compounds for more than …
Epicutaneous sensitization in the development of food allergy: what is the evidence and how can this be prevented?
There is increasing evidence regarding the importance of allergic sensitization through the
skin. In this review, we provide an overview of the atopic march and immune mechanism …
skin. In this review, we provide an overview of the atopic march and immune mechanism …
Mechanisms of allergen-specific immunotherapy and allergen tolerance
abstract Allergen-specific immunotherapy (AIT) is the mainstay treatment for the cure of
allergic disorders, with depicted efficacy and safety by several trials and meta-analysis. AIT …
allergic disorders, with depicted efficacy and safety by several trials and meta-analysis. AIT …
Interleukins 4 and 13 in asthma: key pathophysiologic cytokines and druggable molecular targets
Interleukins (IL)-4 and-13 play a pivotal role in the pathobiology of type-2 asthma. Indeed, IL-
4 is crucially involved in Th2 cell differentiation, immunoglobulin (Ig) class switching and …
4 is crucially involved in Th2 cell differentiation, immunoglobulin (Ig) class switching and …