The pediatrician plays a major role in helping optimize bone health in children and
adolescents. This clinical report reviews normal bone acquisition in infants, children, and …

Juvenile idiopathic arthritis is a broad term that describes a clinically heterogeneous group
of arthritides of unknown cause, which begin before 16 years of age. This term …

The emergence of large-scale genomic, chemical and pharmacological data provides new
opportunities for drug discovery and repositioning. In this work, we develop a computational …

Offering up-to-date, comprehensive coverage of disease progression, diagnosis,
management, and prognosis, Textbook of Pediatric Rheumatology is the definitive reference …

Bisphosphonate therapy is the mainstay of pharmacological intervention in young people
with skeletal fragility. The evidence of its use in a variety of conditions remains limited …

The purpose of the current article is to summarize the evidence‐based medical
complications and treatments that are both common and unique to adolescents with …

In recent years, the issue of low bone density in children and adolescents has attracted
much attention. The classical definition of osteoporosis should be valid at any age, yet its …

Context: As awareness of osteoporosis in childhood has increased, so have pressures to
consider use of the pharmacological agents used to treat osteoporosis in adults. This review …

Osteopenia is a serious medical complication of anorexia nervosa, with no known effective
treatment. We conducted a double-blinded, randomized trial comparing alendronate (10 mg …

Very few studies on bone mineral density and bone metabolism in Duchenne muscular
dystrophy (DMD) have been reported. DMD is a severe, progressive muscular disease …