[HTML][HTML] Regulatory mechanisms of circular RNAs during human mesenchymal stem cell osteogenic differentiation

C Mazziotta, G Badiale, CF Cervellera, M Tognon… - Theranostics, 2024 - ncbi.nlm.nih.gov
Human osteogenic differentiation is a complex and well-orchestrated process which
involves a plethora of molecular players and cellular processes. A growing number of …

STAT3-mediated osteogenesis and osteoclastogenesis in osteoporosis

X Hou, F Tian - Cell Communication and Signaling, 2022 - Springer
Osteoporosis is a common skeletal disease with marked bone loss, deterioration of the bone
microstructure and bone fragility. An abnormal bone remodelling cycle with relatively …

Circ_0114581 promotes osteogenic differentiation of BMSCs via the MiR-155-5p/HNRNPA3 axis

H Li, C Wang, J Yao, Y Jin, X Song, Q Meng, J Wu… - Life Sciences, 2023 - Elsevier
Osteoporosis (OP) is a common metabolic bone disease characterized by deterioration of
bone tissue structure, reduction of bone mass, and susceptibility to fracture. More and new …

[HTML][HTML] Implications and theragnostic potentials of circular RNAs in rheumatic diseases

AA Abbas, HA Abdulkader, R Giordo… - International Journal of …, 2023 - Elsevier
Circular RNAs (circRNAs), a class of non-coding RNAs (ncRNAs), are highly stable and
ubiquitous molecules that exhibit tissue-specific expression. Accumulating evidence has …

Identification of serum exosome-derived circRNA-miRNA-TF-mRNA regulatory network in postmenopausal osteoporosis using bioinformatics analysis and validation …

Q Dong, Z Han, L Tian - Frontiers in endocrinology, 2022 - frontiersin.org
Background Osteoporosis is one of the most common systemic metabolic bone diseases,
especially in postmenopausal women. Circular RNA (circRNA) has been implicated in …

Fine‐tuning osteoclastogenesis: An insight into the cellular and molecular regulation of osteoclastogenesis

A Anwar, L Sapra, N Gupta, RP Ojha… - Journal of cellular …, 2023 - Wiley Online Library
Osteoclasts, the bone‐resorbing cells, are essential for the bone remodeling process and
are involved in the pathophysiology of several bone‐related diseases. The extensive corpus …

Engineered cell-overexpression of circular RNA hybrid hydrogels promotes healing of calvarial defects

M Zhang, Y He, X Zhang, S Gan, X Xie, Z Zheng… - Biomaterials …, 2023 - pubs.rsc.org
Craniomaxillofacial bone defects seriously affect the physical and mental health of patients.
Bone marrow mesenchymal stem cells (BMSCs) are “gold standard” cells used for bone …

Regulation of Wnt signaling by non-coding RNAs during osteoblast differentiation

I Saranya, RL Akshaya, N Selvamurugan - Differentiation, 2022 - Elsevier
Bone is a rigid, mineralized connective tissue that constitutes part of the skeleton in most
vertebrate animals. Bone remodeling is a complex process that involves the coordination of …

Circular RNA ITCH: an emerging multifunctional regulator

K Su, Q Yi, X Dai, O Liu - Biomolecules, 2022 - mdpi.com
In the last decade, numerous circRNAs were discovered by virtue of the RNA-Seq
technique. With the deepening of experimental research, circRNAs have brought to light the …

Therapeutic approach of natural products that treat osteoporosis by targeting epigenetic modulation

G Zhang, Z Liu, Z Li, B Zhang, P Yao, Y Qiao - Frontiers in Genetics, 2023 - frontiersin.org
Osteoporosis (OP) is a metabolic disease that affects bone, resulting in a progressive
decrease in bone mass, quality, and micro-architectural degeneration. Natural products …