Helicobacter pylori and molecular events in precancerous gastric lesions

G Nardone, A Rocco… - Alimentary pharmacology …, 2004 - Wiley Online Library
Gastric cancer can be divided into intestinal type and diffuse type that differ substantially in
epidemiology and pathogenesis. The most important aetiological factor associated both with …

Helicobacter pylori infection and gastric cancer

T Matysiak-Budnik, F Mégraud - European journal of cancer, 2006 - Elsevier
The pathogenesis of gastric cancer (GC) includes a sequence of events that begins with
Helicobacter pylori-induced chronic superficial gastritis, progressing towards atrophic …

Histologic and serum risk markers for noncardia early gastric cancer

A Shiotani, H Iishi, N Uedo… - … journal of cancer, 2005 - Wiley Online Library
Corpus dominant gastritis and intestinal metaplasia (IM) are considered markers of
increased risk of gastric carcinoma. The aim of our study was to determine serum and …

'Senescence‐associated'β‐galactosidase activity in the upper gastrointestinal tract

JJ Going, RC Stuart, M Downie… - The Journal of …, 2002 - Wiley Online Library
Abstract β‐galactosidase activity at pH 6 is associated in vitro with senescence and cellular
death, but in vivo data are sparse. This study undertook firstly to map 'senescence …

Pattern of expression of beta-defensins in oral squamous cell carcinoma

Y Abiko, J Mitamura, M Nishimura, T Muramatsu… - Cancer letters, 1999 - Elsevier
Human β-defensin (hBD)-1 and hBD-2 are antimicrobial peptides that have been detected in
certain types of epithelia, including the skin and oral epithelia. It has been suggested that …

Gastric cancer

M Asaka, AR Sepulveda, T Sugiyama… - … pylori: physiology and …, 2001 - Wiley Online Library
Gastric cancer is one of the most common malignancies in the world, although the incidence
and mortality rate have been decreasing in recent decades. The association between …

[HTML][HTML] Coordinate increase of telomerase activity and c-Myc expression in Helicobacter pylori-associated gastric diseases

GX Zhang, YH Gu, ZQ Zhao, SF Xu… - World journal of …, 2004 - ncbi.nlm.nih.gov
AIM: To detect the telomerase activity and c-Myc expression in gastric diseases and to
examine the relation between these values and Helicobacter pylori (H pylori) as a risk factor …

The gastritis connection: prevention and early detection of gastric neoplasms

RM Genta - Journal of clinical gastroenterology, 2003 - journals.lww.com
Most gastric polyps, adenocarcinomas, carcinoids, and B cell lymphomas arise on a gastric
mucosa damaged by long-standing chronic gastritis. The most common form of chronic …

[HTML][HTML] Fatores genéticos e ambientais envolvidos na carciogênese gástrica

ACG César, AE Silva, EH Tajara - Arquivos de Gastroenterologia, 2002 - SciELO Brasil
RACIONAL: O câncer de estômago é o segundo tipo mais comum de neoplasia no mundo.
A carcinogênese de estômago é processo de múltiplos passos, podendo manifestar-se em …

[HTML][HTML] Gastric cancer development after the successful eradication of Helicobacter pylori

K Uno, K Iijima, T Shimosegawa - World journal of gastrointestinal …, 2016 - ncbi.nlm.nih.gov
Gastric cancer (GC) develops as a result of inflammation-associated carcinogenesis due to
Helicobacter pylori (H. pylori) infection and subsequent defects in genetic/epigenetic events …