A systematic review of closed head injury models of mild traumatic brain injury in mice and rats

CN Bodnar, KN Roberts, EK Higgins… - Journal of …, 2019 - liebertpub.com
Mild TBI (mTBI) is a significant health concern. Animal models of mTBI are essential for
understanding mechanisms, and pathological outcomes, as well as to test therapeutic …

[HTML][HTML] Mechanosensation in traumatic brain injury

CE Keating, DK Cullen - Neurobiology of disease, 2021 - Elsevier
Traumatic brain injury (TBI) is distinct from other neurological disorders because it is
induced by a discrete event that applies extreme mechanical forces to the brain. This review …

Structural neuroimaging in sport-related concussion

ED Bigler - International journal of psychophysiology, 2018 - Elsevier
Structural neuroimaging of athletes who have sustained a sports-related concussion (SRC)
can be viewed as either standard clinical imaging or with advanced neuroimaging methods …

[HTML][HTML] A role for the amygdala in impairments of affective behaviors following mild traumatic brain injury

TA McCorkle, JR Barson, R Raghupathi - Frontiers in behavioral …, 2021 - frontiersin.org
Mild traumatic brain injury (TBI) results in chronic affective disorders such as depression,
anxiety, and fear that persist up to years following injury and significantly impair the quality of …

Enhanced post-traumatic headache-like behaviors and diminished contribution of peripheral CGRP in female rats following a mild closed head injury

D Bree, K Mackenzie, J Stratton, D Levy - Cephalalgia, 2020 - journals.sagepub.com
Introduction Females are thought to have increased risk of developing post-traumatic
headache following a traumatic head injury or concussion. However, the processes …

Approaches to monitor circuit disruption after traumatic brain injury: frontiers in preclinical research

G Krishna, JA Beitchman, CE Bromberg… - International journal of …, 2020 - mdpi.com
Mild traumatic brain injury (TBI) often results in pathophysiological damage that can manifest
as both acute and chronic neurological deficits. In an attempt to repair and reconnect …

Juvenile mild traumatic brain injury elicits distinct spatiotemporal astrocyte responses

T Clément, JB Lee, A Ichkova, B Rodriguez‐Grande… - Glia, 2020 - Wiley Online Library
Mild‐traumatic brain injury (mTBI) represents~ 80% of all emergency room visits and
increases the probability of developing long‐term cognitive disorders in children. To date …

Microstructural tissue changes in a rat model of mild traumatic brain injury

K Chary, O Narvaez, RA Salo… - Frontiers in …, 2021 - frontiersin.org
Our study investigates the potential of diffusion MRI (dMRI), including diffusion tensor
imaging (DTI), fixel-based analysis (FBA) and neurite orientation dispersion and density …

Cumulative strain-based metrics for predicting subconcussive head impact exposure–related imaging changes in a cohort of American youth football players

LE Miller, JE Urban, MA Espeland, MP Walkup… - Journal of …, 2022 - thejns.org
OBJECTIVE Youth football athletes are exposed to repetitive subconcussive head impacts
during normal participation in the sport, and there is increasing concern about the long-term …

Diffusion tensor imaging of the evolving response to mild traumatic brain injury in rats

WS Hoogenboom, TG Rubin, K Ye… - Journal of …, 2019 - journals.sagepub.com
Mild traumatic brain injury (mTBI), also known as concussion, is a serious public health
challenge. Although most patients recover, a substantial minority suffers chronic disability …