Recent advancements in the molecular genetics of left ventricular noncompaction cardiomyopathy
X Dong, P Fan, T Tian, Y Yang, Y Xiao, K Yang, Y Liu… - Clinica Chimica …, 2017 - Elsevier
Left ventricular noncompaction cardiomyopathy (LVNC) is a myocardial disorder
characterized by prominent and excessive trabeculations with deep recesses in the …
characterized by prominent and excessive trabeculations with deep recesses in the …
[HTML][HTML] Selectivity in genetic association with sub-classified migraine in women
Migraine can be sub-classified not only according to presence of migraine aura (MA) or
absence of migraine aura (MO), but also by additional features accompanying migraine …
absence of migraine aura (MO), but also by additional features accompanying migraine …
[HTML][HTML] The differences in the developmental stages of the cardiomyocytes and endothelial cells in human and mouse embryos at the single-cell level
C Liu, NY Shao - International Journal of Molecular Sciences, 2024 - mdpi.com
Our research focuses on expression patterns in human and mouse embryonic
cardiomyocytes and endothelial cells at the single-cell level. We analyzed single-cell …
cardiomyocytes and endothelial cells at the single-cell level. We analyzed single-cell …
Zebrafish as a model of cardiac disease
RN Wilkinson, C Jopling, FJM van Eeden - Progress in molecular biology …, 2014 - Elsevier
The zebrafish has been rapidly adopted as a model for cardiac development and disease.
The transparency of the embryo, its limited requirement for active oxygen delivery, and ease …
The transparency of the embryo, its limited requirement for active oxygen delivery, and ease …
Heritability and genome‐wide association study of blood pressure in Chinese adult twins
J Chen, W Wang, Z Li, C Xu, X Tian… - Molecular genetics & …, 2021 - Wiley Online Library
Background Blood pressure (BP) is an independent and important factor for chronic
diseases such as cardiovascular diseases and diabetes. Methods We firstly conducted twin …
diseases such as cardiovascular diseases and diabetes. Methods We firstly conducted twin …
[HTML][HTML] Anti-cancer therapy is associated with long-term epigenomic changes in childhood cancer survivors
N Robinson, J Casement, MJ Gunter… - British journal of …, 2022 - nature.com
Background Childhood cancer survivors (CCS) exhibit significantly increased chronic
diseases and premature death. Abnormalities in DNA methylation are associated with …
diseases and premature death. Abnormalities in DNA methylation are associated with …
Genetics and disease of ventricular muscle
D Fatkin, CE Seidman… - Cold Spring …, 2014 - perspectivesinmedicine.cshlp.org
Cardiomyopathies are a heterogeneous group of heart muscle diseases associated with
heart failure, arrhythmias, and death. Genetic variation has a critical role in the pathogenesis …
heart failure, arrhythmias, and death. Genetic variation has a critical role in the pathogenesis …
Identification of three novel genetic variations associated with electrocardiographic traits (QRS duration and PR interval) in East Asians
KW Hong, JE Lim, JW Kim, Y Tabara… - Human molecular …, 2014 - academic.oup.com
The electrocardiogram has several advantages in detecting cardiac arrhythmia—it is readily
available, noninvasive and cost-efficient. Recent genome-wide association studies have …
available, noninvasive and cost-efficient. Recent genome-wide association studies have …
[HTML][HTML] Spen deficiency interferes with Connexin 43 expression and leads to heart failure in zebrafish
M Rattka, S Westphal, BM Gahr, S Just… - Journal of Molecular and …, 2021 - Elsevier
Genome-wide association studies identified Spen as a putative modifier of cardiac function,
however, the precise function of Spen in the cardiovascular system is not known yet. Here …
however, the precise function of Spen in the cardiovascular system is not known yet. Here …
A review of migraine genetics: gathering genomic and transcriptomic factors
Migraine is a common and complex neurologic disorder that affects approximately 15–18%
of the general population. Although the cause of migraine is unknown, some genetic studies …
of the general population. Although the cause of migraine is unknown, some genetic studies …