Zika virus in the female genital tract
N Prisant, L Bujan, H Benichou, PH Hayot… - The Lancet infectious …, 2016 - thelancet.com
In the landmark Stop Antibiotics on Procalcitonin guidance Study (SAPS), Evelien De Jong
and colleagues1 showed that a procalcitonin-guided stopping rule was highly efficient and …
and colleagues1 showed that a procalcitonin-guided stopping rule was highly efficient and …
Zika virus infection in mice causes panuveitis with shedding of virus in tears
Zika virus (ZIKV) is an emerging flavivirus that causes congenital abnormalities and Guillain-
Barré syndrome. ZIKV infection also results in severe eye disease characterized by optic …
Barré syndrome. ZIKV infection also results in severe eye disease characterized by optic …
Pathogenesis and virulence of flavivirus infections
The Flavivirus genus consists of> 70 members including several that are considered
significant human pathogens. Flaviviruses display a broad spectrum of diseases that can be …
significant human pathogens. Flaviviruses display a broad spectrum of diseases that can be …
Highly efficient maternal-fetal Zika virus transmission in pregnant rhesus macaques
SM Nguyen, KM Antony, DM Dudley, S Kohn… - PLoS …, 2017 - journals.plos.org
Infection with Zika virus (ZIKV) is associated with human congenital fetal anomalies. To
model fetal outcomes in nonhuman primates, we administered Asian-lineage ZIKV …
model fetal outcomes in nonhuman primates, we administered Asian-lineage ZIKV …
Microbial communities in placentas from term normal pregnancy exhibit spatially variable profiles
LA Parnell, CM Briggs, B Cao, O Delannoy-Bruno… - Scientific reports, 2017 - nature.com
The placenta is the principal organ nurturing the fetus during pregnancy and was
traditionally considered to be sterile. Recent work has suggested that the placenta harbours …
traditionally considered to be sterile. Recent work has suggested that the placenta harbours …
Chloroquine, a FDA-approved drug, prevents Zika virus infection and its associated congenital microcephaly in mice
Zika virus (ZIKV) has become a global public health emergency due to its rapidly expanding
range and its ability to cause severe congenital defects such as microcephaly. However …
range and its ability to cause severe congenital defects such as microcephaly. However …
Zika virus: an emerging challenge to public health worldwide
Zika virus (ZIKV) is a mosquito-borne virus that was first isolated from Zika forest, Uganda, in
1947. Since its inception, major and minor outbreaks have been documented from several …
1947. Since its inception, major and minor outbreaks have been documented from several …
Identification of Zika virus epitopes reveals immunodominant and protective roles for dengue virus cross-reactive CD8+ T cells
CD8+ T cells play an important role in controlling Flavivirus infection, including Zika virus
(ZIKV). Here, we have identified 25 HLA-B* 0702-restricted epitopes and 1 HLA-A* 0101 …
(ZIKV). Here, we have identified 25 HLA-B* 0702-restricted epitopes and 1 HLA-A* 0101 …
The many faces of the flavivirus NS5 protein in antagonism of type I interferon signaling
SM Best - Journal of virology, 2017 - Am Soc Microbiol
The vector-borne flaviviruses cause severe disease in humans on every inhabited continent
on earth. Their transmission by arthropods, particularly mosquitoes, facilitates large …
on earth. Their transmission by arthropods, particularly mosquitoes, facilitates large …
Azithromycin protects against Zika virus infection by upregulating virus-induced type I and III interferon responses
C Li, S Zu, YQ Deng, D Li, K Parvatiyar… - Antimicrobial agents …, 2019 - Am Soc Microbiol
Azithromycin (AZM) is a widely used antibiotic, with additional antiviral and anti-inflammatory
properties that remain poorly understood. Although Zika virus (ZIKV) poses a significant …
properties that remain poorly understood. Although Zika virus (ZIKV) poses a significant …