[HTML][HTML] The emergence, genomic diversity and global spread of SARS-CoV-2

J Li, S Lai, GF Gao, W Shi - Nature, 2021 - nature.com
Since the first cases of COVID-19 were documented in Wuhan, China in 2019, the world has
witnessed a devastating global pandemic, with more than 238 million cases, nearly 5 million …

Next generation sequencing of SARS-CoV-2 genomes: challenges, applications and opportunities

M Chiara, AM D'Erchia, C Gissi… - Briefings in …, 2021 - academic.oup.com
Various next generation sequencing (NGS) based strategies have been successfully used in
the recent past for tracing origins and understanding the evolution of infectious agents …

[HTML][HTML] Activity of convalescent and vaccine serum against SARS-CoV-2 Omicron

JM Carreño, H Alshammary, J Tcheou, G Singh… - Nature, 2022 - nature.com
Abstract The Omicron (B. 1.1. 529) variant of severe acute respiratory syndrome coronavirus
2 (SARS-CoV-2) was initially identified in November 2021 in South Africa and Botswana, as …

[HTML][HTML] SARS-CoV-2 D614G spike mutation increases entry efficiency with enhanced ACE2-binding affinity

S Ozono, Y Zhang, H Ode, K Sano, TS Tan… - Nature …, 2021 - nature.com
The causative agent of the COVID-19 pandemic, SARS-CoV-2, is steadily mutating during
continuous transmission among humans. Such mutations can occur in the spike (S) protein …

[HTML][HTML] Sixteen novel lineages of SARS-CoV-2 in South Africa

H Tegally, E Wilkinson, RJ Lessells, J Giandhari… - Nature medicine, 2021 - nature.com
The first severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in South
Africa was identified on 5 March 2020, and by 26 March the country was in full lockdown …

[HTML][HTML] Mutations in SARS-CoV-2 variants of concern link to increased spike cleavage and virus transmission

A Escalera, AS Gonzalez-Reiche, S Aslam, I Mena… - Cell host & …, 2022 - cell.com
SARS-CoV-2 lineages have diverged into highly prevalent variants termed" variants of
concern"(VOCs). Here, we characterized emerging SARS-CoV-2 spike polymorphisms in …

[HTML][HTML] SARS-CoV-2 mRNA vaccination induces functionally diverse antibodies to NTD, RBD, and S2

F Amanat, M Thapa, T Lei, SMS Ahmed, DC Adelsberg… - Cell, 2021 - cell.com
In this study we profiled vaccine-induced polyclonal antibodies as well as plasmablast-
derived mAbs from individuals who received SARS-CoV-2 spike mRNA vaccine. Polyclonal …

The evolving SARS-CoV-2 epidemic in Africa: Insights from rapidly expanding genomic surveillance

H Tegally, JE San, M Cotten, M Moir, B Tegomoh… - Science, 2022 - science.org
Investment in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) sequencing
in Africa over the past year has led to a major increase in the number of sequences that …

[HTML][HTML] Persistence of symptoms and quality of life at 35 days after hospitalization for COVID-19 infection

LG Jacobs, E Gourna Paleoudis, D Lesky-Di Bari… - PloS one, 2020 - journals.plos.org
Background Characterizing the prevalence and persistence of symptoms associated with
COVID-19 infection following hospitalization and their impact is essential to planning post …

[HTML][HTML] COVID-19 outbreak—New York City, February 29–June 1, 2020

CN Thompson - MMWR. Morbidity and mortality weekly report, 2020 - cdc.gov
Approximately 203,000 cases of laboratory-confirmed COVID-19 were reported in NYC
during the first 3 months of the pandemic. The crude fatality rate among confirmed cases …