Progesterone receptor membrane component 1 (PGRMC1) is a multi-functional protein with
a heme-binding moiety related to that of cytochrome b 5, which is a putative progesterone …

Abstract Progesterone Receptor Membrane Component 1 (PGRMC1) is a heme-binding
protein that has been implicated in a wide range of cell and tissue functions, including …

Background Increased expression of the progesterone receptor membrane component 1
(PGRMC1) has been linked to multiple cancers, including breast cancer. Despite being a …

Progesterone receptor membrane component 1 (PGRMC1) is a heme-binding protein
implicated in a wide range of cellular functions. We previously showed that PGRMC1 binds …

Cancer is one of the most common causes of death worldwide, and its development is a
result of the complex interaction of genetic factors, environmental cues, and aging. Hormone …

Progesterone Receptor Membrane Component 1 (PGRMC1) is a tumour-promoting factor in
several types of cancer but its role in brain tumours is poorly characterized thus far. Our …

Progesterone and its synthetic analogues, progestins, participate in the regulation of cell
differentiation, proliferation and cell cycle progression. Progestins are usually applied for …

Steroid hormones bind receptors in the cell nucleus and in the cell membrane. The most
widely studied class of steroid hormone receptors are the nuclear receptors, named for their …

Objective: Expression of progesterone receptor membrane component 1 (PGRMC1) has
been shown to be higher in breast cancer than normal tissue. We have previously shown …

Progesterone receptor membrane component (PGRMC) proteins play important roles in
tumor growth, progression, and chemoresistance, of which PGRMC1 is the best …