How times have changed! A cornucopia of antigens for membranous nephropathy

TN Caza, LF Al-Rabadi, LH Beck Jr - Frontiers in Immunology, 2021 - frontiersin.org
The identification of the major target antigen phospholipase A2 receptor (PLA2R) in the
majority of primary (idiopathic) cases of membranous nephropathy (MN) has been followed …

The ameliorative effect of mahuang fuzi and shenzhuo decoction on membranous nephropathy of rodent model is associated with autophagy and wnt/β-catenin …

Y Gao, H Dai, N Zhang, H Jiang, Z Zhang… - Frontiers in …, 2022 - frontiersin.org
The increased incidence of membranous nephropathy (MN) has made it the most common
pathological type of primary nephrotic syndrome in adults in China. According to the theory …

Cytokines network in primary membranous nephropathy

Q Zhao, H Dai, Y Hu, H Jiang, Z Feng, W Liu… - International …, 2022 - Elsevier
There have been extensive studies on the immunological mechanism of primary
membranous nephropathy (PMN). Autoantibodies, being the end product of humoral auto …

[HTML][HTML] A Comprehensive Phenotypic and Functional Immune Analysis Unravels Circulating Anti–Phospholipase A2 Receptor Antibody Secreting Cells in …

C Cantarelli, M Jarque, A Angeletti, J Manrique… - Kidney international …, 2020 - Elsevier
Introduction Primary membranous nephropathy (MN) is characterized by the presence of
antipodocyte antibodies, but studies describing phenotypic and functional abnormalities in …

New-onset and relapsed membranous nephropathy post SARS-CoV-2 and COVID-19 vaccination

Q Ma, X Li, G Xu - Viruses, 2022 - mdpi.com
Since the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) outbreak and
COVID-19 vaccination, new-onset and relapsed clinical cases of membranous nephropathy …

A novel insight into the role of PLA2R and THSD7A in membranous nephropathy

P Zhang, W Huang, Q Zheng, J Tang… - Journal of …, 2021 - Wiley Online Library
Membranous nephropathy (MN) is an organ‐restricted autoimmune disease mainly caused
by circulating autoantibodies against podocyte antigens, including the M‐type …

Epigallocatechin Gallate Relieved PM2. 5‐Induced Lung Fibrosis by Inhibiting Oxidative Damage and Epithelial‐Mesenchymal Transition through AKT/mTOR …

Z Zhongyin, W Wei, X Juan… - Oxidative Medicine and …, 2022 - Wiley Online Library
Oxidative damage and epithelial‐mesenchymal transition (EMT) are main pathological
processes leading to the development of PM2. 5‐induced lung fibrosis. Epigallocatechin …

[HTML][HTML] Experimental models for elderly patients with membranous nephropathy: Application and advancements

X Tang, H Dai, Y Hu, W Liu, Q Zhao, H Jiang… - Experimental …, 2024 - Elsevier
Membranous nephropathy (MN) occurs predominantly in middle-aged and elderly
individuals and ranks among the most prevalent etiologies of elderly nephrotic syndrome. As …

Course monitoring of membranous nephropathy: Both autoantibodies and podocytes require multidimensional attention

W Liu, G Huang, H Rui, J Geng, H Hu, Y Huang… - Autoimmunity …, 2022 - Elsevier
A variety of podocyte antigens have been identified in human membranous nephropathy
(MN), which is divided into various antigen-dominated subtypes, confirming the concept that …

Progress in understanding primary glomerular disease: insights from urinary proteomics and in-depth analyses of potential biomarkers based on bioinformatics

L Ge, J Liu, B Lin, X Qin - Critical Reviews in Clinical Laboratory …, 2023 - Taylor & Francis
Chronic kidney disease (CKD) has become a global public health challenge. While primary
glomerular disease (PGD) is one of the leading causes of CKD, the specific pathogenesis of …