Oxidative stress and impaired oligodendrocyte precursor cell differentiation in neurological disorders

J Spaas, L Van Veggel, M Schepers, A Tiane… - Cellular and Molecular …, 2021 - Springer
Oligodendrocyte precursor cells (OPCs) account for 5% of the resident parenchymal central
nervous system glial cells. OPCs are not only a back-up for the loss of oligodendrocytes that …

Role of oxidative damage in alzheimer's disease and neurodegeneration: From pathogenic mechanisms to biomarker discovery

FR Buccellato, M D'Anca, C Fenoglio, E Scarpini… - Antioxidants, 2021 - mdpi.com
Alzheimer's disease (AD) is a neurodegenerative disorder accounting for over 50% of all
dementia patients and representing a leading cause of death worldwide for the global …

The role of microRNAs in neurodegenerative diseases: a review

S Li, Z Lei, T Sun - Cell Biology and Toxicology, 2023 - Springer
MicroRNAs (miRNAs) are non-coding RNAs which are essential post-transcriptional gene
regulators in various neuronal degenerative diseases and playact a key role in these …

The relation of the brain-derived neurotrophic factor with microRNAs in neurodegenerative diseases and ischemic stroke

C Eyileten, L Sharif, Z Wicik, D Jakubik… - Molecular …, 2021 - Springer
Brain-derived neurotrophic factor (BDNF) is a member of the neurotrophin family of growth
factors that plays a crucial role in the development of the nervous system while supporting …

The role of exosomal microRNAs and oxidative stress in neurodegenerative diseases

X Wang, Y Zhou, Q Gao, D Ping, Y Wang… - Oxidative medicine …, 2020 - Wiley Online Library
Neurodegenerative diseases including Alzheimer's disease and Parkinson's disease are
aging‐associated diseases with irreversible damage of brain tissue. Oxidative stress is …

Aging, oxidative stress and degenerative diseases: mechanisms, complications and emerging therapeutic strategies

MR Chaudhary, S Chaudhary, Y Sharma, TA Singh… - Biogerontology, 2023 - Springer
Aging accompanied by several age-related complications, is a multifaceted inevitable
biological progression involving various genetic, environmental, and lifestyle factors. The …

Neuroprotective effects and therapeutic potential of the citrus flavonoid hesperetin in neurodegenerative diseases

JA Evans, P Mendonca, KFA Soliman - Nutrients, 2022 - mdpi.com
Neurodegenerative disorders affect more than fifty million Americans each year and
represent serious health threats as the population ages. Neuroinflammation and oxidative …

Common and novel markers for measuring inflammation and oxidative stress ex vivo in research and clinical practice—which to use regarding disease outcomes?

A Menzel, H Samouda, F Dohet, S Loap, MS Ellulu… - Antioxidants, 2021 - mdpi.com
Many chronic conditions such as cancer, chronic obstructive pulmonary disease, type-2
diabetes, obesity, peripheral/coronary artery disease and auto-immune diseases are …

Inflammation: A new look at an old problem

E Gusev, Y Zhuravleva - International Journal of Molecular Sciences, 2022 - mdpi.com
Pro-inflammatory stress is inherent in any cells that are subject to damage or threat of
damage. It is defined by a number of universal components, including oxidative stress …

RNA and oxidative stress in Alzheimer's disease: focus on microRNAs

A Nunomura, G Perry - Oxidative medicine and cellular …, 2020 - Wiley Online Library
Oxidative stress (OS) is one of the major pathomechanisms of Alzheimer's disease (AD),
which is closely associated with other key events in neurodegeneration such as …