[HTML][HTML] The role of Raman spectroscopy within quantitative metabolomics

C Lima, H Muhamadali… - Annual Review of …, 2021 - annualreviews.org
Ninety-four years have passed since the discovery of the Raman effect, and there are
currently more than 25 different types of Raman-based techniques. The past two decades …

Quantitative stimulated Raman scattering microscopy: promises and pitfalls

B Manifold, D Fu - Annual Review of Analytical Chemistry, 2022 - annualreviews.org
Since its first demonstration, stimulated Raman scattering (SRS) microscopy has become a
powerful chemical imaging tool that shows promise in numerous biological and biomedical …

A versatile deep learning architecture for classification and label-free prediction of hyperspectral images

B Manifold, S Men, R Hu, D Fu - Nature machine intelligence, 2021 - nature.com
Hyperspectral imaging is a technique that provides rich chemical or compositional
information not regularly available to traditional imaging modalities such as intensity …

Denoising of stimulated Raman scattering microscopy images via deep learning

B Manifold, E Thomas, AT Francis, AH Hill… - Biomedical optics …, 2019 - opg.optica.org
Stimulated Raman scattering (SRS) microscopy is a label-free quantitative chemical imaging
technique that has demonstrated great utility in biomedical imaging applications ranging …

Cellular imaging using stimulated Raman scattering microscopy

AH Hill, D Fu - Analytical chemistry, 2019 - ACS Publications
Cellular imaging is an active area of research that enables researchers to monitor cellular
dynamics, as well as responses to various external stimuli (physiological stress, exogenous …

Characterizing silicone oil-induced protein aggregation with stimulated raman scattering imaging

B Wong, X Zhao, Y Su, H Ouyang… - Molecular …, 2023 - ACS Publications
Particles in biopharmaceutical products present high risks due to their detrimental impacts
on product quality and safety. Identification and quantification of particles in drug products …

[HTML][HTML] Raman micro-spectroscopy for accurate identification of primary human bronchial epithelial cells

JM Surmacki, BJ Woodhams, A Haslehurst… - Scientific reports, 2018 - nature.com
Live cell Raman micro-spectroscopy is emerging as a promising bioanalytical technique for
label-free discrimination of a range of different cell types (eg cancer cells and fibroblasts) …

Broadband hyperspectral stimulated Raman scattering microscopy with a parabolic fiber amplifier source

B Figueroa, W Fu, T Nguyen, K Shin… - Biomedical optics …, 2018 - opg.optica.org
Hyperspectral stimulated Raman scattering (hsSRS) microscopy has recently emerged as a
powerful non-destructive technique for the label-free chemical imaging of biological …

Mapping structural dynamics of proteins with femtosecond stimulated Raman spectroscopy

C Fang, L Tang - Annual Review of Physical Chemistry, 2020 - annualreviews.org
The structure–function relationships of biomolecules have captured the interest and
imagination of the scientific community and general public since the field of structural …

Seeing is Believing: Developing Multimodal Metabolic Insights at the Molecular Level

RS Chadha, JA Guerrero, L Wei… - ACS Central Science, 2024 - ACS Publications
This outlook explores how two different molecular imaging approaches might be combined
to gain insight into dynamic, subcellular metabolic processes. Specifically, we discuss how …