Biological barriers are essential for the maintenance of homeostasis in health and disease.
Breakdown of the intestinal barrier is an essential aspect of the pathophysiology of …

Distinction between Crohn's disease of the colon-rectum and ulcerative colitis or
inflammatory bowel disease (IBD) type unclassified can be of pivotal importance for a …

Background Human proteins are widely used as drug targets. Integration of large-scale
protein-level genome-wide association studies (GWAS) and disease-related GWAS has thus …

Background Dietary fiber is fermented in the lower gastrointestinal tract, potentially
impacting the microbial ecosystem and thus may improve elements of cognition and brain …

We studied the effects of intestinal inflammation on pentylenetetrazole (PTZ)-induced
seizures in mice and the effects thereon of some antiepileptic and anti-inflammatory …

Inflammatory bowel diseases (IBD) are chronic inflammatory conditions affecting the
digestive system, comprising two main distinctive entities, ulcerative colitis (UC) and Crohn's …

Recently, the immune system has been identified as one of the possible main bridges which
connect the gut–brain axis. This review aims to examine available evidence on the …

Ulcerative colitis is a chronic inflammatory disease, profoundly affecting the patient's quality
of life and is associated with various complications. Linagliptin, a potent DPP-IV inhibitor …

Psoriasis and the spectrum of inflammatory bowel diseases (IBD) are chronic, inflammatory,
organotropic conditions. The epidemiologic coexistence of these diseases is corroborated …

The brain and the gut are linked together with a complex, bi-path link known as the gut-brain
axis through the central and enteric nervous systems. So, the brain directly affects and …