Spreading depression (SD) is a transient wave of near-complete neuronal and glial
depolarization associated with massive transmembrane ionic and water shifts. It is …

Functional magnetic resonance imaging (fMRI) provides a unique view of the working
human mind. The blood-oxygen-level-dependent (BOLD) signal, detected in fMRI, reflects …

Although modern techniques such as two-photon microscopy can now provide cellular-level
three-dimensional imaging of the intact living brain, the speed and fields of view of these …

First introduced in the 1980s, laser speckle contrast imaging is a powerful tool for full-field
imaging of blood flow. Recently laser speckle contrast imaging has gained increased …

Recent advances in optical technologies such as multi-photon microscopy and optogenetics
have revolutionized our ability to record and manipulate neuronal activity. Combining optical …

Optical brain imaging has seen 30 years of intense development, and has grown into a rich
and diverse field. In-vivo imaging using light provides unprecedented sensitivity to functional …

Simultaneous transcranial imaging of two functional parameters, the total concentration of
hemoglobin and the hemoglobin oxygen saturation, in the rat brain in vivo is realized …

Laser speckle contrast imaging (LSCI) has emerged over the past decade as a powerful, yet
simple, method for imaging of blood flow dynamics in real time. The rapid adoption of LSCI …

Diffuse optical tomography (DOT) is an attractive approach for evaluating stroke physiology.
It provides hemodynamic and metabolic imaging with unique potential for continuous …

Laser Speckle Contrast Imaging (LSCI) is a wide field of view, non scanning optical
technique for observing blood flow. Speckles are produced when coherent light scattered …