The study of the gut microbiome has increasingly revealed an important role in modulating
brain function and mental health. In this review, we underscore specific pathways and …

Anhedonia is considered a core feature of major depressive disorder, and the dopamine
system plays a pivotal role in the hedonic deficits described in this disorder. Dopaminergic …

Bipolar affective disorder is a common neuropsychiatric disorder. Although its
neurobiological underpinnings are incompletely understood, the dopamine hypothesis has …

Major depressive disorder (MDD) is a highly prevalent psychiatric disorder and a major
cause of disability worldwide. This neurological condition is commonly associated with …

Despite being considered primarily a mood disorder, major depressive disorder (MDD) is
characterized by cognitive and decision making deficits. Recent research has employed …

Adolescence is a developmental period associated with vast neural and behavioral changes
which are accompanied by altered sensitivity to stimuli, both stressful and rewarding …

This work provides an overview of the most consistent alterations in bipolar disorder (BD),
attempting to unify them in an internally coherent working model of the pathophysiology of …

Depression is a frequently encountered non-motor feature of Parkinson's disease (PD) and it
can have a significant impact on patient's quality of life. Considering the differential …

Dirnagl and Endres Found in Translation 1511 has failed to deliver evidence for a clinical
benefit of any of the neuroprotectants tested. Recent examples include erythropoietin, 18 …

Background Parkinson's disease (PD) is a chronic neurodegenerative condition that is
characterized by motor symptoms as a result of dopaminergic degeneration, particularly in …