Microbial biofilm: a review on formation, infection, antibiotic resistance, control measures, and innovative treatment

S Sharma, J Mohler, SD Mahajan, SA Schwartz… - Microorganisms, 2023 - mdpi.com
Biofilm is complex and consists of bacterial colonies that reside in an exopolysaccharide
matrix that attaches to foreign surfaces in a living organism. Biofilm frequently leads to …

Antimicrobial properties of chitosan and chitosan derivatives in the treatment of enteric infections

D Yan, Y Li, Y Liu, N Li, X Zhang, C Yan - Molecules, 2021 - mdpi.com
Antibiotics played an important role in controlling the development of enteric infection.
However, the emergence of antibiotic resistance and gut dysbiosis led to a growing interest …

Staphylococcus aureus Biofilm: Morphology, Genetics, Pathogenesis and Treatment Strategies

M Idrees, S Sawant, N Karodia, A Rahman - International Journal of …, 2021 - mdpi.com
Staphylococcus aureus is a nosocomial bacterium causing different infectious diseases,
ranging from skin and soft tissue infections to more serious and life-threatening infections …

[HTML][HTML] Bacterial biofilm eradication agents: a current review

AD Verderosa, M Totsika, KE Fairfull-Smith - Frontiers in chemistry, 2019 - frontiersin.org
Most free-living bacteria can attach to surfaces and aggregate to grow into multicellular
communities encased in extracellular polymeric substances called biofilms. Biofilms are …

A review of the microbial production of bioactive natural products and biologics

JV Pham, MA Yilma, A Feliz, MT Majid… - Frontiers in …, 2019 - frontiersin.org
A variety of organisms, such as bacteria, fungi, and plants, produce secondary metabolites,
also known as natural products. Natural products have been a prolific source and an …

Revisiting the virulence hallmarks of Pseudomonas aeruginosa: a chronicle through the perspective of quorum sensing

J Chadha, K Harjai, S Chhibber - Environmental microbiology, 2022 - Wiley Online Library
Pseudomonas aeruginosa is an opportunistic pathogen and the leading cause of mortality
among immunocompromised patients in clinical setups. The hallmarks of virulence in P …

[HTML][HTML] Biofilms: Formation, drug resistance and alternatives to conventional approaches

R Mirghani, T Saba, H Khaliq, J Mitchell, L Do… - AIMS …, 2022 - ncbi.nlm.nih.gov
Biofilms are aggregates of bacteria, in most cases, which are resistant usually to broad-
spectrum antibiotics in their typical concentrations or even in higher doses. A trend of …

Fatty acids as antibiofilm and antivirulence agents

P Kumar, JH Lee, H Beyenal, J Lee - Trends in microbiology, 2020 - cell.com
Fatty acids (FAs) have emerged as a potential alternative to conventional antibiotics. Since
many microbes respond differently to a variety of natural and synthetic FAs, substantial …

Antibiotic adjuvants: rescuing antibiotics from resistance

GD Wright - Trends in microbiology, 2016 - cell.com
Rooted in the mechanism of action of antibiotics and subject to bacterial evolution, antibiotic
resistance is difficult and perhaps impossible to overcome. Nevertheless, strategies can be …

Chitosan and their derivatives: Antibiofilm drugs against pathogenic bacteria

F Khan, DTN Pham, SF Oloketuyi… - Colloids and Surfaces B …, 2020 - Elsevier
Biofilm formed by several pathogenic bacteria results in the development of resistance
against antimicrobial compounds. The polymeric materials present in the biofilm architecture …