[HTML][HTML] 3D printing technologies in personalized medicine, nanomedicines, and biopharmaceuticals
3D printing technologies enable medicine customization adapted to patients' needs. There
are several 3D printing techniques available, but majority of dosage forms and medical …
are several 3D printing techniques available, but majority of dosage forms and medical …
[HTML][HTML] The functional and clinical roles of liquid biopsy in patient-derived models
Z Zhu, E Hu, H Shen, J Tan, S Zeng - Journal of Hematology & Oncology, 2023 - Springer
The liquid biopsy includes the detection of circulating tumor cells (CTCs) and CTC clusters
in blood, as well as the detection of, cell-free DNA (cfDNA)/circulating tumor DNA (ctDNA) …
in blood, as well as the detection of, cell-free DNA (cfDNA)/circulating tumor DNA (ctDNA) …
Tubuloid culture enables long-term expansion of functional human kidney tubule epithelium from iPSC-derived organoids
FA Yousef Yengej, J Jansen… - Proceedings of the …, 2023 - National Acad Sciences
Kidney organoids generated from induced pluripotent stem cells (iPSC) have proven
valuable for studies of kidney development, disease, and therapeutic screening. However …
valuable for studies of kidney development, disease, and therapeutic screening. However …
Global Meta-Analysis of Organoid and Organ-on-Chip Research.
J Shoji, RP Davis, CL Mummery… - Advanced healthcare …, 2023 - duo.uio.no
Organoids and cells in organ‐on‐chip platforms replicate higher‐level anatomical,
physiological, or pathological states of tissues and organs. These technologies are widely …
physiological, or pathological states of tissues and organs. These technologies are widely …
[HTML][HTML] Application of microfluidic chips in the simulation of the urinary system microenvironment
C Hou, Y Gu, W Yuan, W Zhang, X Xiu, J Lin, Y Gao… - Materials Today Bio, 2023 - Elsevier
The urinary system, comprising the kidneys, ureters, bladder, and urethra, has a unique
mechanical and fluid microenvironment, which is essential to the urinary system growth and …
mechanical and fluid microenvironment, which is essential to the urinary system growth and …
[HTML][HTML] Innovating spinal muscular atrophy models in the therapeutic era
I Signoria, WL van der Pol… - Disease Models & …, 2023 - journals.biologists.com
Spinal muscular atrophy (SMA) is a severe, monogenetic, neuromuscular disease. A
thorough understanding of its genetic cause and the availability of robust models has led to …
thorough understanding of its genetic cause and the availability of robust models has led to …
[HTML][HTML] Mesenchymal Stromal Cell-Derived Extracellular Vesicles for Vasculopathies and Angiogenesis: Therapeutic Applications and Optimization
Y Zhu, ZF Liao, MH Mo, XD Xiong - Biomolecules, 2023 - mdpi.com
Extracellular vesicles (EVs), as part of the cellular secretome, have emerged as essential
cell–cell communication regulators in multiple physiological and pathological processes …
cell–cell communication regulators in multiple physiological and pathological processes …
[HTML][HTML] Organ-on-a-chip: an emerging research platform
R Nithin, A Aggarwal, AB Sravani, P Mallya… - Organogenesis, 2023 - ncbi.nlm.nih.gov
In drug development, conventional preclinical and clinical testing stages rely on cell cultures
and animal experiments, but these methods may fall short of fully representing human …
and animal experiments, but these methods may fall short of fully representing human …
3D printed tubulointerstitium chip as an in vitro testing platform
Chronic kidney disease (CKD) ranks as the twelfth leading cause of death worldwide with
limited treatment options. The development of in vitro models replicating defined segments …
limited treatment options. The development of in vitro models replicating defined segments …
[PDF][PDF] Tubuloid differentiation to model the human distal nephron and collecting duct in health and disease
FAY Yengej, CP Casellas, CME Ammerlaan… - Cell Reports, 2024 - cell.com
Organoid technology is rapidly gaining ground for studies on organ (patho) physiology.
Tubuloids are long-term expanding organoids grown from adult kidney tissue or urine. The …
Tubuloids are long-term expanding organoids grown from adult kidney tissue or urine. The …