Pathogenicity and virulence of Staphylococcus aureus
Staphylococcus aureus is one of the most frequent worldwide causes of morbidity and
mortality due to an infectious agent. This pathogen can cause a wide variety of diseases …
mortality due to an infectious agent. This pathogen can cause a wide variety of diseases …
Staphylococcus aureus Secreted Toxins and Extracellular Enzymes
K Tam, VJ Torres - Microbiology spectrum, 2019 - Am Soc Microbiol
Staphylococcus aureus is a formidable pathogen capable of causing infections in different
sites of the body in a variety of vertebrate animals, including humans and livestock. A major …
sites of the body in a variety of vertebrate animals, including humans and livestock. A major …
Exploring the Role of Staphylococcus aureus in Inflammatory Diseases
H Chen, J Zhang, Y He, Z Lv, Z Liang, J Chen, P Li… - Toxins, 2022 - mdpi.com
Staphylococcus aureus is a very common Gram-positive bacterium, and S. aureus infections
play an extremely important role in a variety of diseases. This paper describes the types of …
play an extremely important role in a variety of diseases. This paper describes the types of …
Staphylococcus aureus metalloprotease aureolysin cleaves complement C3 to mediate immune evasion
AJ Laarman, M Ruyken, CL Malone… - The Journal of …, 2011 - journals.aai.org
Complement is one of the first host defense barriers against bacteria. Activated complement
attracts neutrophils to the site of infection and opsonizes bacteria to facilitate phagocytosis …
attracts neutrophils to the site of infection and opsonizes bacteria to facilitate phagocytosis …
Corruption of innate immunity by bacterial proteases
J Potempa, RN Pike - Journal of innate immunity, 2009 - karger.com
The innate immune system of the human body has developed numerous mechanisms to
control endogenous and exogenous bacteria and thus prevent infections by these …
control endogenous and exogenous bacteria and thus prevent infections by these …
Extracellular proteases are key mediators of Staphylococcus aureus virulence via the global modulation of virulence‐determinant stability
SL Kolar, J Antonio Ibarra, FE Rivera… - …, 2013 - Wiley Online Library
Staphylococcus aureus is a highly virulent and successful pathogen that causes a diverse
array of diseases. Recently, an increase of severe infections in healthy subjects has been …
array of diseases. Recently, an increase of severe infections in healthy subjects has been …
Intracellular Staphylococcus aureus and host cell death pathways
YM Soe, S Bedoui, TP Stinear… - Cellular …, 2021 - Wiley Online Library
Staphylococcus aureus is a major opportunistic human pathogen that is globally prevalent.
Although S. aureus and humans may have co‐evolved to the point of commensalism, the …
Although S. aureus and humans may have co‐evolved to the point of commensalism, the …
Bacterial proteases and virulence
Bacterial pathogens rely on proteolysis for variety of purposes during the infection process.
In the cytosol, the main proteolytic players are the conserved Clp and Lon proteases that …
In the cytosol, the main proteolytic players are the conserved Clp and Lon proteases that …
Phagocytosis of Staphylococcus aureus by Macrophages Exerts Cytoprotective Effects Manifested by the Upregulation of Antiapoptotic Factors
J Koziel, A Maciag-Gudowska, T Mikolajczyk… - PloS one, 2009 - journals.plos.org
It is becoming increasingly apparent that Staphylococcus aureus are able to survive
engulfment by macrophages, and that the intracellular environment of these host cells …
engulfment by macrophages, and that the intracellular environment of these host cells …
Staphylococcal proteases aid in evasion of the human complement system
M Jusko, J Potempa, T Kantyka, E Bielecka… - Journal of innate …, 2014 - karger.com
Staphylococcus aureus is an opportunistic pathogen that presents severe health care
concerns due to the prevalence of multiple antibiotic-resistant strains. New treatment …
concerns due to the prevalence of multiple antibiotic-resistant strains. New treatment …