SUMMARY HIV-1 DNA exists in nonintegrated linear and circular episomal forms and as
integrated proviruses. In patients with plasma viremia, most peripheral blood mononuclear …

Human APOBEC3 (apolipoprotein B mRNA-editing catalytic polypeptide-like 3) enzymes
are capable of inhibiting a wide range of endogenous and exogenous viruses using …

As novel SARS-CoV-2 variants with different patterns of spike protein mutations have
emerged, the susceptibility of these variants to neutralization by antibodies has been rapidly …

Higher accessibility and decreasing costs of next generation sequencing (NGS), availability
of commercial kits, and development of dedicated analysis pipelines, have allowed an …

Next-generation sequencing (NGS) is increasingly used for HIV-1 drug resistance
genotyping. NGS methods have the potential for a more sensitive detection of low …

Antiretroviral therapy (ART) has improved the lifespan of people living with HIV. However,
their immune system remains in a state of sustained activation/inflammation, which favors …

Background: There are an increasing number of articles focused on the prevalence and
clinical impact of pretreatment HIV drug resistance (PDR) detected by Sanger sequencing …

Objectives As many disparities in the clinical use of HIV DNA sequencing are observed, a
DELPHI-type consensus was initiated in France to homogenize use, techniques and …

Introduction Although most laboratories are capable of employing established protocols to
perform full-genome SARS-CoV-2 sequencing, many are unable to assess sequence …

Objective: To describe the occurrence of HIV drug resistance mutations (DRMs) in both
intact and defective HIV-1 cell-associated DNA (HIV-1 CAD) among early-treated infants …