There is an immediate need to address long‐standing questions about the reproductive
health of girls and women with sickle cell disease (SCD). There are many SCD‐related …

Osteonecrosis, a form of ischemic bone injury that leads to degenerative joint disease,
affects∼ 30% of people with sickle cell disease. Although osteonecrosis most commonly …

Abstract Background The Gaucher Investigative Therapy Evaluation is a national clinical
cohort of 250 patients aged 5–87 years with Gaucher disease in the United Kingdom—an …

Acute lymphoblastic leukemia (ALL), currently the most common pediatric leukemia, has a
high curability rate of up to 90%. Endocrine disorders are highly prevalent in children with …

Human parvovirus B19 causes life-threatening anemia due to transient red cell aplasia
(TRCA) in individuals with sickle cell disease (SCD). Children with SCD experiencing …

The bone is one of the most commonly affected organs in sickle cell disease (SCD).
Repeated ischemia, oxidative stress and inflammation within the bone is largely responsible …

Intro: Microvascular occlusions caused by sickle cell disease (SCD) can affect all ocular and
orbital structures (Figure 1). Sickle cell retinopathy (SCR) is the most common ophthalmic …

Bone involvement of sickle cell disease (SCD) patients varies from acute clinical
manifestations of painful vaso-occlusive crises or osteomyelitis to more chronic affection of …

Objective Mechanisms underlying the oral outcomes in sickle cell anemia (HbSS) have
been less explored. This study aimed to investigate the association of morbimortality …

Background: Patients with pediatric leukemia and sickle cell disease are at risk for
developing osteonecrosis (ON), a disease that can result in pain, loss of function, and …