[HTML][HTML] Licochalcone B induced apoptosis and autophagy in osteosarcoma tumor cells via the inactivation of PI3K/AKT/mTOR pathway
Z Huang, G Jin - Biological and Pharmaceutical Bulletin, 2022 - jstage.jst.go.jp
Licochalcone B (LicB) is a flavonoid derived from the Chinese medicinal herb Glycyrrhiza
uralensis Fisch. Several previous studies have demonstrated the wide range of …
uralensis Fisch. Several previous studies have demonstrated the wide range of …
2'-Hydroxychalcone Induces Autophagy and Apoptosis in Breast Cancer Cells via the Inhibition of the NF-κB Signaling Pathway: In Vitro and In Vivo Studies
X Wang, Y Liang, B Zhang, L He, W Li, W Zhang, C Li… - Nutrients, 2024 - mdpi.com
2'-Hydroxychalcone is a hydroxyl derivative of chalcones, which are biosynthetic precursors
of flavonoids and rich in the human diet. The anticancer activity of 2'-hydroxychalcone has …
of flavonoids and rich in the human diet. The anticancer activity of 2'-hydroxychalcone has …
Targeting autophagy in disease: recent advances in drug discovery
D Kim, HY Hwang, HJ Kwon - Expert Opinion on Drug Discovery, 2020 - Taylor & Francis
Introduction Small molecules targeting autophagy have been highly implicated as new
therapeutic agents to treat diseases of interest. With the increasing demand for autophagy …
therapeutic agents to treat diseases of interest. With the increasing demand for autophagy …
Cytotoxic and antitumor activity of lactaptin in combination with autophagy inducers and inhibitors
AV Bagamanshina, OS Troitskaya… - BioMed Research …, 2019 - Wiley Online Library
Autophagy is a degradative process in which cellular organelles and proteins are recycled
to restore homeostasis and cellular metabolism. Autophagy can be either a prosurvival or a …
to restore homeostasis and cellular metabolism. Autophagy can be either a prosurvival or a …
LT-IIc, a bacterial type II heat-labile enterotoxin, induces specific lethality in triple negative breast cancer cells by modulation of autophagy and induction of apoptosis …
P Masso-Welch, S Girald Berlingeri… - International Journal of …, 2018 - mdpi.com
Triple negative breast cancer (TNBC) remains a serious health problem with poor prognosis
and limited therapeutic options. To discover novel approaches to treat TNBC, we screened …
and limited therapeutic options. To discover novel approaches to treat TNBC, we screened …
Radix Sophorae Flavescentis inhibits proliferation and induces apoptosis of AGS human gastric cancer cells
JS Kim, SJ Shin, JN Kim, MJ Kwon… - Molecular …, 2019 - spandidos-publications.com
Traditional herbal medicines are being increasingly used worldwide to treat cancer. Radix
Sophorae Flavescentis (RSF) is a Chinese herb, which has numerous pharmacological …
Sophorae Flavescentis (RSF) is a Chinese herb, which has numerous pharmacological …
Bioactive flavonoid apigenin and its nanoformulations: a promising hope for diabetes and cancer
B Mukherjee, S Banerjee, L Mondal… - Nanomedicine for …, 2020 - Springer
Apigenin, an important flavones, belongs to the subclass of flavonoids. Apigenin proved its
potency towards different dreadful pathophysiological conditions, including diabetes and …
potency towards different dreadful pathophysiological conditions, including diabetes and …
BIX-01294, a G9a inhibitor, suppresses cell proliferation by inhibiting autophagic flux in nasopharyngeal carcinoma cells
Q Li, L Wang, D Ji, X Bao, G Tan, X Liang… - Investigational New …, 2021 - Springer
G9a, a histone methyltransferase, has been found to be upregulated in a range of tumor
tissues, and contributes to tumor growth and metastasis. However, the impact of G9a …
tissues, and contributes to tumor growth and metastasis. However, the impact of G9a …
[HTML][HTML] Expression of cyclin-dependent kinase 9 is positively correlated with the autophagy level in colon cancer
L Zheng, J Lu, DL Kong - World Journal of Gastrointestinal …, 2024 - ncbi.nlm.nih.gov
BACKGROUND Cyclin-dependent kinase 9 (CDK9) expression and autophagy in colorectal
cancer (CRC) tissues has not been widely studied. CDK9, a key regulator of transcription …
cancer (CRC) tissues has not been widely studied. CDK9, a key regulator of transcription …
[HTML][HTML] 2, 5-dimethyl celecoxib induces apoptosis and autophagy via activation of ROS/JNK axis in nasopharyngeal carcinoma cells
T Tan, X Fu, J Qu, M Zhang, H Chen, Y Wang… - Aging (Albany …, 2021 - ncbi.nlm.nih.gov
dimethyl celecoxib (DMC), a close derivative of celecoxib, has also been reported to have
anticancer effects. However, the effects and underlying molecular mechanisms of DMC with …
anticancer effects. However, the effects and underlying molecular mechanisms of DMC with …