Despite the steady increase in the number of studies focusing on the development of tissue
engineered constructs, solutions delivered to the clinic are still limited. Specifically, the lack …

Skin injuries and in particular, chronic wounds, are one of the major prevalent medical
problems, worldwide. Due to the pivotal role of angiogenesis in tissue regeneration …

The vasculature is an essential component of the circulatory system that plays a vital role in
the development, homeostasis, and disease of various organs in the human body. The …

The effects of a microgravity environment on the myriad types of immune cells present within
the human body have been assessed both by bench-scale simulation and suborbital …

Macrophages are primarily known as phagocytic immune cells, but they also play a role in
diverse processes, such as morphogenesis, homeostasis and regeneration. In this review …

Heterotopic ossification (HO) is a double‐edged sword. Pathological HO presents as an
undesired clinical complication, whereas controlled heterotopic bone formation by synthetic …

Implant surface topography has been proven to determine the fate of adhered macrophage
polarization, which is closely related to the cytoskeletal arrangement during adhesion. Our …

Vascularization of tissue engineering constructs is an urgent need for delivering oxygen and
nutrients and promoting tissue remodeling. As we all know, almost all implanted …

Fabrication of large-scale engineered tissues requires extensive vascularization to support
tissue survival and function. Here, we report a modular fabrication approach, by stacking of …

The effects of spaceflight, including prolonged exposure to microgravity, can have significant
effects on the immune system and human health. Altered immune cell function can lead to …