Exogenous hormones are used by more than a hundred million women worldwide as oral
contraceptives or for postmenopausal hormone replacement. Oral contraceptives increase …

Although venous thrombosis has been traditionally associated with stasis and
hypercoagulability, arterial thrombosis is mainly associated with heightened platelet …

There is now strong experimental evidence that tissue factor pathway inhibitor (TFPI) is a
critical inhibitor to modulate tissue factor–induced coagulation, but the role of TFPI as a risk …

The generation of thrombin by the prothrombinase complex constitutes an essential step in
hemostasis, with thrombin being crucial for the amplification of blood coagulation, fibrin …

The incidence of venous thrombosis associated with estrogen treatment in male-to-female
(M→ F) transsexuals is considerably higher with administration of oral ethinyl estradiol (EE) …

Estrogen and progestins have been used by millions of women as effective combined
contraceptives. The safety of hormonal contraceptives has been documented by years of …

Pulmonary delivery of lipid-based nanotherapeutics by inhalation presents an
advantageous alternative to oral and intravenous routes of administration that avoids …

Obesity has emerged as a global health issue that is associated with wide spectrum of
disorders, including coronary artery disease, diabetes mellitus, hypertension, stroke, and …

Venous thromboembolism is a serious disorder because of its potential complications, such
as pulmonary embolism and the post-thrombotic syndrome. Inherited determinants of …

Hundreds of millions of women worldwide use either oral contraceptives or postmenopausal
hormone replacement. The use of oral contraceptives leads to an increased risk of venous …