Encapsulins

TW Giessen - Annual review of biochemistry, 2022 - annualreviews.org
Subcellular compartmentalization is a defining feature of all cells. In prokaryotes,
compartmentalization is generally achieved via protein-based strategies. The two main …

[HTML][HTML] Clinical characteristics, diagnosis, treatment, and mortality rate of TB/COVID-19 coinfectetd patients: a systematic review

M Koupaei, A Naimi, N Moafi, P Mohammadi… - Frontiers in …, 2021 - frontiersin.org
Introduction: Novel coronavirus (Covid-19) and tuberculosis (TB) are the newest and oldest
global threats, respectively. In the Covid-19 era, due to the health system's focus on the …

[HTML][HTML] Tackling Drug-Resistant Tuberculosis: New Challenges from the Old Pathogen Mycobacterium tuberculosis

G Mancuso, A Midiri, S De Gaetano, E Ponzo… - Microorganisms, 2023 - mdpi.com
Antibiotics have played a crucial role in the reduction in the incidence of TB globally as
evidenced by the fact that before the mid-20th century, the mortality rate within five years of …

[HTML][HTML] Large-scale computational discovery and analysis of virus-derived microbial nanocompartments

MP Andreas, TW Giessen - Nature Communications, 2021 - nature.com
Encapsulins are a class of microbial protein compartments defined by the viral HK97-fold of
their capsid protein, self-assembly into icosahedral shells, and dedicated cargo loading …

[HTML][HTML] The impact of Mycobacterium tuberculosis complex in the environment on one health approach

H Zhang, M Liu, W Fan, S Sun, X Fan - Frontiers in Public Health, 2022 - frontiersin.org
Tuberculosis caused by the Mycobacterium tuberculosis complex (MTBC) has become one
of the leading causes of death in humans and animals. Current research suggests that the …

[HTML][HTML] Metabolomic profiling reveals bacterial metabolic adaptation strategies and new metabolites

H Wang, LPS de Carvalho - Current Opinion in Chemical Biology, 2023 - Elsevier
How has metabolomics helped our understanding of infectious diseases? With the threat of
antimicrobial resistance to human health around the world, metabolomics has emerged as a …

[HTML][HTML] Application of lipid-based nanocarriers for antitubercular drug delivery: a review

AB Buya, BA Witika, AM Bapolisi, C Mwila… - Pharmaceutics, 2021 - mdpi.com
The antimicrobial drugs currently used for the management of tuberculosis (TB) exhibit poor
bioavailability that necessitates prolonged treatment regimens and high dosing frequency to …

[HTML][HTML] Presence of foodborne bacteria in wild boar and wild boar meat—a literature survey for the period 2012–2022

C Altissimi, C Noé-Nordberg, D Ranucci, P Paulsen - Foods, 2023 - mdpi.com
The wild boar is an abundant game species with high reproduction rates. The management
of the wild boar population by hunting contributes to the meat supply and can help to avoid a …

[HTML][HTML] Mycobacterium tuberculosis in a Trap: The Role of Neutrophil Extracellular Traps in Tuberculosis

LHA Cavalcante-Silva, FS Almeida… - International journal of …, 2023 - mdpi.com
Mycobacterium tuberculosis complex causes tuberculosis (TB), a disease that causes
pulmonary inflammation but can also affect other tissues. Despite macrophages having a …

Nanotechnology and tuberculosis: An old disease with new treatment strategies

DC dos Santos Macêdo, IDL Cavalcanti, JB de Souza… - Tuberculosis, 2022 - Elsevier
Tuberculosis is an intracellular infectious disease caused by Mycobacterium tuberculosis,
which mainly affects the lungs. Especially in patients infected by the Human …