LncRNA‐mediated posttranslational modifications and reprogramming of energy metabolism in cancer

YT Tan, JF Lin, T Li, JJ Li, RH Xu… - Cancer …, 2021 - Wiley Online Library
Altered metabolism is a hallmark of cancer, and the reprogramming of energy metabolism
has historically been considered a general phenomenon of tumors. It is well recognized that …

The role of noncoding RNAs in Parkinson's disease: biomarkers and associations with pathogenic pathways

MC Kuo, SCH Liu, YF Hsu, RM Wu - Journal of biomedical science, 2021 - Springer
The discovery of various noncoding RNAs (ncRNAs) and their biological implications is a
growing area in cell biology. Increasing evidence has revealed canonical and noncanonical …

Noncoding RNA processing by DIS3 regulates chromosomal architecture and somatic hypermutation in B cells

B Laffleur, J Lim, W Zhang, Y Chen, E Pefanis… - Nature …, 2021 - nature.com
Noncoding RNAs are exquisitely titrated by the cellular RNA surveillance machinery for
regulating diverse biological processes. The RNA exosome, the predominant 3′ RNA …

Long non-coding RNAs and cancer metastasis: Molecular basis and therapeutic implications

H Ming, B Li, L Zhou, A Goel, C Huang - Biochimica et Biophysica Acta …, 2021 - Elsevier
Cancer metastasis, defined by the epithelial to mesenchymal transition (EMT) of tumor cells,
disseminates from the primary site to progressively colonize in distant tissues, and accounts …

NcPath: A novel platform for visualization and enrichment analysis of human non-coding RNA and KEGG signaling pathways

Z Li, Y Zhang, J Fang, Z Xu, H Zhang, M Mao… - …, 2023 - academic.oup.com
Non-coding RNAs play important roles in transcriptional processes and participate in the
regulation of various biological functions, in particular miRNAs and lncRNAs. Despite their …

LncRNA MIAT correlates with immune infiltrates and drug reactions in hepatocellular carcinoma

L Peng, Y Chen, Q Ou, X Wang, N Tang - International …, 2020 - Elsevier
Long non-coding RNA (lncRNA) is a kind of important molecules involved in the formation of
immune landscape in tumor microenvironment. However, there are few studies on the …

Mechanism of noncoding RNA-associated N6-methyladenosine recognition by an RNA processing complex during IgH DNA recombination

L Nair, W Zhang, B Laffleur, MK Jha, J Lim, H Lee… - Molecular cell, 2021 - cell.com
Immunoglobulin heavy chain (IgH) locus-associated G-rich long noncoding RNA (SμGLT) is
important for physiological and pathological B cell DNA recombination. We demonstrate that …

Structural basis for RNA surveillance by the human nuclear exosome targeting (NEXT) complex

MR Puno, CD Lima - Cell, 2022 - cell.com
RNA quality control relies on co-factors and adaptors to identify and prepare substrates for
degradation by ribonucleases such as the 3′ to 5′ ribonucleolytic RNA exosome. Here …

Long non-coding RNAs in plants: emerging modulators of gene activity in development and stress responses

L Chen, QH Zhu, K Kaufmann - Planta, 2020 - Springer
Main conclusion Long non-coding RNAs modulate gene activity in plant development and
stress responses by various molecular mechanisms. Abstract Long non-coding RNAs …

RNA exosome drives early B cell development via noncoding RNA processing mechanisms

B Laffleur, CR Batista, W Zhang, J Lim, B Yang… - Science …, 2022 - science.org
B cell development is linked to successful V (D) J recombination, allowing B cell receptor
expression and ultimately antibody secretion for adaptive immunity. Germline noncoding …