Gonadotropin-releasing hormone in the ovary

C Metallinou, B Asimakopoulos… - Reproductive …, 2007 - journals.sagepub.com
Gonadotropin-releasing hormone (GnRH) plays a pivotal role in the physiology of
reproduction in mammals. GnRH acts by binding to the GnRH receptor (GnRHR). In …

Gonadotropin-releasing hormone regulates spine density via its regulatory role in hippocampal estrogen synthesis

J Prange-Kiel, H Jarry, M Schoen, P Kohlmann… - The Journal of cell …, 2008 - rupress.org
Spine density in the hippocampus changes during the estrus cycle and is dependent on the
activity of local aromatase, the final enzyme in estrogen synthesis. In view of the abundant …

G-protein-coupled receptors in aldosterone-producing adenomas: a potential cause of hyperaldosteronism

P Ye, B Mariniello, F Mantero… - Journal of …, 2007 - joe.bioscientifica.com
The source of aldosterone in 30–40% of patients with primary hyperaldosteronism (PA) is
unilateral aldosterone-producing adenoma (APA). The mechanisms causing elevated …

Biophysical studies and in vitro effects of tumor cell lines of cannabidiol and its cyclodextrin inclusion complexes

K Hatziagapiou, K Bethanis, E Koniari, E Christoforides… - Pharmaceutics, 2022 - mdpi.com
Phytocannabinoids possess anticancer properties, as established in vitro and in vivo.
However, they are characterized by high lipophilicity. To improve the properties of …

Mechanisms underlying the tissue-specific and regulated activity of the Gnrhr promoter in mammals

AL Schang, B Quérat, V Simon, G Garrel… - Frontiers in …, 2012 - frontiersin.org
The GnRH receptor (GnRHR) plays a central role in the development and maintenance of
reproductive function in mammals. Following stimulation by GnRH originating from the …

GnRH protective effects against amyloid β-induced cognitive decline: a potential role of the 17β-estradiol

L Marbouti, M Zahmatkesh, E Riahi… - Molecular and Cellular …, 2020 - Elsevier
Introduction The 17β-estradiol (E2) enhances hippocampal dendritic spine synapses,
facilitates learning processes, and exerts neuroprotection. Brain estrogen decline has been …

促性腺激素释放激素受体(GnRHR) 基因多态性及其与山羊产羔数的相关性分析

黄杨河, 王凭青, 杨力, 储明星, 张宝云, 邓腊梅, 谭颖… - 畜牧兽医学报, 2012 - xmsyxb.com
本研究采用候选基因法对与繁殖性能有关的遗传标记进行筛选, 旨在为山羊高产仔数的标记辅助
选择提供确切的遗传依据. 参考牛的促性腺激素释放激素受体(Gonadotropin releasing …

GnRHR gene polymorphisms and their effects on reproductive performance in Chinese goats

XP An, D Han, JX Hou, G Li, JG Wang, MM Yang… - Small Ruminant …, 2009 - Elsevier
In this study, polymorphisms in the goat GnRHR gene exon 1 were detected by PCR-SSCP
and DNA sequencing methods in 786 individuals from two different goat breeds. Two …

Neuron navigator 3 alterations in nervous system tumors associate with tumor malignancy grade and prognosis

E Carlsson, K Krohn, K Ovaska… - Genes …, 2013 - Wiley Online Library
Copy number changes or reduced expression of the Neuron navigator 3 (NAV3) gene
occurs in neuroblastomas and malignancies of epithelial or lymphoid origin. To elucidate …

Protein kinase Cα-induced derepression of the human luteinizing hormone receptor gene transcription through ERK-mediated release of HDAC1/Sin3A repressor …

M Liao, Y Zhang, ML Dufau - Molecular Endocrinology, 2008 - academic.oup.com
LH receptor (LHR) gene transcription is subject to repression/derepression through various
modes and multiple effectors. Epigenetic silencing and activation of the LHR is achieved …