Background The use of biomarkers for prostate cancer screening, diagnosis and prognosis
has the potential to improve the clinical management of the patients. Owing to inherent …

Prostate cancer is the second highest cause of cancer mortality after lung tumours. In USA it
affects about 2.8 million men and the incidence increases with age in many countries …

Fatty acid β-oxidation (FAO) is the main bioenergetic pathway in human prostate cancer
(PCa) and a promising novel therapeutic vulnerability. Here we demonstrate therapeutic …

The year 2015 marks the 50th anniversary since the discovery of the anticancer potential of
cisplatin and it remains just as useful now as it did back then, especially for the treatment of …

As prostate cancer (PCa) is one of the most commonly diagnosed cancer worldwide,
identifying potential prognostic biomarkers is crucial. In this study, the survival information …

Prostate cancer (PCa) is a leading cause of male cancer-related deaths. A significant
fraction of prostate tumors are very aggressive, often metastasizing to bone, causing …

Castration-resistant prostate cancer (CRPC) is defined by tumor microenvironment
heterogeneity affecting intrinsic cellular mechanisms including dysregulated androgen …

Background Circular RNAs (circRNAs) have been proven to function as pivotal regulators in
cancer occurrence and progression. However, the function of circ_0006404 (circRNA …

OBJECTIVE: The aim of this study was to investigate the inhibitory role of microRNA-1299
(miR-1299) in prostate cancer, and to explore the possible underlying mechanism …

Simple Summary Prostate cancer cells produce lipids via the activation of a specific pathway
called fatty acid synthesis, also known as De novo lipogenesis. This pathway is essential for …