Objectives We aimed to provide the most updated estimates on the global burden of
inflammatory bowel disease (IBD) to improve management strategies. Design We extracted …

CD38 is a molecule that can act as an enzyme, with NAD-depleting and intracellular
signaling activity, or as a receptor with adhesive functions. CD38 can be found expressed …

Omics technologies have rapidly evolved with the unprecedented potential to shape
precision medicine. Novel omics approaches are imperative toallow rapid and accurate data …

Background Intestinal dysbiosis is associated with inflammatory bowel disease (IBD).
Ulcerative colitis (UC) and Crohn's disease (CD), two subtypes of IBD, are characterized by …

Intercellular cross talk between cancer cells and stromal and immune cells is essential for
tumor progression and metastasis. Extracellular vesicles and particles (EVPs) are a …

Crohn's disease (CD) is a chronic relapsing disorder of the gastrointestinal tract and
represents one of the main entities of inflammatory bowel disease (IBD). CD affects …

The intestinal barrier is composed of a complex cell network defining highly
compartmentalized and specialized structures. Here, we use spatial transcriptomics to …

Exosomes are spherical lipid bilayer vesicles composed of lipids, proteins and nucleic acids
that deliver signaling molecules through a vesicular transport system to regulate the function …

In inflammatory bowel disease (IBD), intestinal mucosa cell and intestinal epithelial cell are
severely damaged, and then their susceptibility to bacteria increases, so many commensal …

Inflammatory bowel disease (IBD) is a result of a complex interplay between genes, host
immune response, gut microbiota, and environmental factors. As one of the crucial …