Allogeneic hematopoietic stem cell transplantation is a definitive therapy for a variety of
disorders. One of the complications is acute graft-versus-host disease (aGVHD), which has a …

Exosomes contain multiple bioactive molecules and maintain the connection between cells.
Recent advances in exosome-based therapeutics have witnessed unprecedented …

Ocular graft-versus-host-disease (GVHD) remains a significant clinical complication after
allogeneic hematopoietic stem cell transplantation. Impaired visual function, pain, and other …

Purpose To validate the international chronic ocular graft-versus-host disease (GVHD)
diagnostic criteria (ICCGVHD) compared to the National Institute of Health diagnostic criteria …

Ocular graft-versus-host disease (GVHD) is a major complication after allogeneic
hematopoietic stem cell transplantation. Ocular GVHD affects recipients' visual function and …

Dry eye disease (DED) is a broad term that includes a diverse group of clinical disorders.
Aqueous-deficient dry eye (ADDE), a subtype of DED, is characterized by decreased tear …

Proper sight is not possible without a smooth, transparent cornea, which is highly exposed to
environmental threats. The abundant corneal nerves are interspersed with epithelial cells in …

Neutrophil extracellular traps (NETs) are net-like complexes expelled from neutrophils,
composing cell-free deoxyribonucleic acid (DNA), histones, and neutrophil granule proteins …

Inflammation is an important driver of dry eye disease (DED) pathogenesis. An initial insult
that results in the loss of tear film homeostasis can initiate a nonspecific innate immune …

Graft-versus-host disease (GVHD) is characterized by tissue inflammation in the host
following an allogeneic hematopoietic cell transplantation (HCT). The pathophysiology is …