Epidemiology and infectivity of Plasmodium falciparum and Plasmodium vivax gametocytes in relation to malaria control and elimination

T Bousema, C Drakeley - Clinical microbiology reviews, 2011 - Am Soc Microbiol
Malaria remains a major cause of morbidity and mortality in the tropics, with Plasmodium
falciparum responsible for the majority of the disease burden and P. vivax being the …

Malaria parasite clearance

NJ White - Malaria journal, 2017 - Springer
Following anti-malarial drug treatment asexual malaria parasite killing and clearance
appear to be first order processes. Damaged malaria parasites in circulating erythrocytes …

New antimalarial drugs

J Wiesner, R Ortmann, H Jomaa… - Angewandte Chemie …, 2003 - Wiley Online Library
Approximately 40% of the world population live in areas with the risk of malaria. Each year,
300–500 million people suffer from acute malaria, and 0.5–2.5 million die from the disease …

Resistance to Therapies for Infection by Plasmodium vivax

JK Baird - Clinical microbiology reviews, 2009 - Am Soc Microbiol
The gravity of the threat posed by vivax malaria to public health has been poorly
appreciated. The widely held misperception of Plasmodium vivax as being relatively …

Mixed-species malaria infections in humans

M Mayxay, S Pukrittayakamee, PN Newton… - Trends in …, 2004 - cell.com
Mixed-species malaria infections are often not recognized or underestimated. In Asia,
surveys usually report that< 2% of infections are mixed, whereas therapeutic studies in vivax …

Tetracyclines in malaria

T Gaillard, M Madamet, B Pradines - Malaria journal, 2015 - Springer
Malaria, a parasite vector-borne disease, is one of the greatest health threats in tropical
regions, despite the availability of malaria chemoprophylaxis. The emergence and rapid …

Clindamycin as an antimalarial drug: review of clinical trials

B Lell, PG Kremsner - Antimicrobial agents and chemotherapy, 2002 - Am Soc Microbiol
Clinical trials from the 1970s and 1980s have shown the efficacy, safety, and practicability of
the treatment of Plasmodium falciparum malaria with clindamycin. Two reviews from the …

Using Amplicon Deep Sequencing to Detect Genetic Signatures of Plasmodium vivax Relapse

JT Lin, NJ Hathaway, DL Saunders… - The Journal of …, 2015 - academic.oup.com
Plasmodium vivax infections often recur due to relapse of hypnozoites from the liver. In
malaria-endemic areas, tools to distinguish relapse from reinfection are needed. We applied …

Targeting the liver stage of malaria parasites: a yet unmet goal

T Rodrigues, M Prudêncio, R Moreira… - Journal of medicinal …, 2012 - ACS Publications
Malaria remains one of the world's most prevalent tropical diseases because of its high
mortality and morbidity burden, as well as its economic and social impacts on the …

Spatio-temporal distribution of Plasmodium falciparum and p. Vivax malaria in Thailand.

G Zhou, J Sirichaisinthop, J Sattabongkot… - The American journal …, 2005 - escholarship.org
Malaria incidence data at the district level from 1997 to 2002 and total malaria case data
from 1965 to 2002 in Thailand were analyzed to determine the spatial and temporal …