The current focus of cardiovascular medicine is on early detection and prevention of
disease, to control the escalating costs of health care. To achieve this goal, novel imaging …

In almost all cardiac diseases, an increase in extracellular matrix (ECM) deposition or
fibrosis occurs, mostly consisting of collagen I. Whereas replacement fibrosis follows …

Advances in cardiovascular molecular imaging have come at a rapid pace over the last
several years. Multiple approaches have been taken to better understand the structural …

Objectives: The purpose of this study was to evaluate the feasibility of noninvasive imaging
of angiotensin II (AT) receptor upregulation in a mouse model of post-myocardial infarction …

Advances in nanoparticle contrast agents for molecular imaging have made magnetic
resonance imaging a promising modality for noninvasive visualization and assessment of …

Objectives: Using molecular imaging techniques, we examined interstitial alterations during
postmyocardial infarction (MI) remodeling and assessed the efficacy of antiangiotensin and …

Introduction The clinical feasibility of noninvasive imaging of interstitial alterations after
myocardial infarction (MI) was assessed using a technetium-99m-labeled RGD imaging …

Molecular imaging is a new and evolving field that employs a targeted approach to
noninvasively assess biologic processes in vivo. By assessing key elements in specific …

Left ventricular remodeling is a key determinant of the clinical course and outcome of
systolic heart failure. The myocardial renin–angiotensin system (RAS) has been closely …

Abstract Purpose of the Review Cardiorenal syndrome (CRS), defined as concomitant heart
and kidney disease, has been a focus of attention for nearly a decade. As more patients …