Plants have long been exploited as a sustainable source of food, flavors, agrochemicals,
colors, therapeutic proteins, bioactive compounds, and stem cell production. However, plant …

Covering: 1976 to 2020. Although constituting a limited chemical family, phytostilbenes
represent an emblematic group of molecules among natural compounds. Ever since their …

Polyketides are a diverse class of molecules sought after for their valuable properties,
including as potential pharmaceuticals. Previously, we demonstrated that the oleaginous …

Resveratrol is a plant secondary metabolite with multiple health-beneficial properties.
Microbial production of resveratrol in model microorganisms requires extensive engineering …

Natural products account for more than 50% of all small-molecule pharmaceutical agents
currently in clinical use. However, low availability often becomes problematic when a …

Flavonoids are secondary metabolites that represent a heterogeneous family of plant
polyphenolic compounds. Recent research has determined that the health benefits of fruits …

Microbial production of fuels and chemicals offers a means by which sustainable product
manufacture can be achieved. In this regard, Yarrowia lipolytica is a unique microorganism …

Cancer is a condition caused by many mechanisms (genetic, immune, oxidation, and
inflammatory). Anticancer therapy aims to destroy or stop the growth of cancer cells …

Squalene is the precursor for triterpene-based natural products and steroids-based drugs. It
has been widely used as pharmaceutical intermediates and personal care products. The …

CRISPR-Cas9 has been widely adopted as the basic toolkit for precise genome-editing and
engineering in various organisms. Alternative to Cas9, Cas12 or Cpf1 uses a simple crRNA …