Objective: Lipodystrophy syndromes are extremely rare disorders of deficient body fat
associated with potentially serious metabolic complications, including diabetes …

Lipodystrophies have been recognized since at least the nineteenth century and, despite
their rarity, tended to attract considerable medical attention because of the severity and …

Lipodystrophy syndromes are rare diseases originating from a generalized or partial loss of
adipose tissue. Adipose tissue dysfunction results from heterogeneous genetic or acquired …

The main function of the nuclear lamina, an intermediate filament meshwork lying primarily
beneath the inner nuclear membrane, is to provide structural scaffolding for the cell nucleus …

Autosomal dominant familial partial lipodystrophy (FPLD) due to mutant LMNA encoding
nuclear lamin A/C is characterized by adipose tissue repartitioning together with multiple …

Traditional risk factors for coronary artery disease (CAD) predict about 50% of the risk of
developing CAD. The Adult Treatment Panel (ATP) III has defined emerging risk factors for …

Lamin A/C proteins are the major components of a thin proteinaceous filamentous
meshwork, the lamina, that underlies the inner nuclear membrane. A few specific mutations …

Lipodystrophies are rare, heterogeneous, genetic or acquired, disorders characterised by
varying degrees of body fat loss and associated metabolic complications, including insulin …

The adipocytes synthesize and store triglycerides as lipid droplets surrounded by various
proteins and phospholipids at its surface. Recently, the molecular basis of some of the …

Abstract Purpose of Review Genetic or acquired lipodystrophies are characterized by
selective loss of body fat along with predisposition towards metabolic complications of …