Chronic diabetic wounds seriously threaten human health due to their intractable nature in a
complex pathological microenvironment that contains oxidative stress, persistent …

Mitochondria in osteoblasts have been demonstrated to play multiple crucial functions in
bone formation from intracellular ATP production to extracellular secretion of mitochondrial …

Bone homeostasis refers to the balance between osteoblast-mediated bone formation and
osteoclast-mediated bone resorption and the maintenance of stable bone mass. SIRT3 is a …

Metabolic alternation is a typical characteristic of insecticide resistance in insects. However,
mechanisms underlying metabolic alternation and how altered metabolism in turn affects …

Knee osteoarthritis (KOA), one of the most common orthopedic disorders concerning the
adult population worldwide, is a condition characterized by progressive destruction of the …

Multiple phenolic substances have been shown to promote SIRT3 expression, however, few
studies have focused on the effects of these phenolics on SIRT3 enzyme activity. This study …

Fluorescence-activated cell sorting (FACS) is a specialized technique to isolate specific cell
subpopulations with a high level of recovery and accuracy. However, the cell sorting …

Background A deterioration in the meat quality of broilers has attracted much more attention
in recent years. L-malic acid (MA) is evidenced to decrease meat drip loss in broilers, but the …

Osteoarthritis (OA) is a prevalent chronic joint disease characterized by articular cartilage
degeneration, pain, and disability. Emerging evidence indicates that mitochondrial quality …

In the nucleus, distinct, discrete spots or regions called “foci” have been identified, each
harboring a specific molecular function. Accurate and efficient quantification of these foci is …