Cryptococcal meningitis diagnostics and screening in the era of point-of-care laboratory testing

R Rajasingham, RM Wake, T Beyene… - Journal of clinical …, 2019 - Am Soc Microbiol
Over the past ten years, standard diagnostics for cryptococcal meningitis in HIV-infected
persons have evolved from culture to India ink to detection of cryptococcal antigen (CrAg) …

[HTML][HTML] Serology anno 2021—fungal infections: from invasive to chronic

C Lass-Flörl, E Samardzic, M Knoll - Clinical Microbiology and Infection, 2021 - Elsevier
Background Diagnosing invasive or chronic fungal infections is a challenge, particularly in
the immunocompromised host. Microscopy and culture remain the reference standard, but …

Low-cost, point-of-care biomarker quantification

F Piorino, AT Patterson, MP Styczynski - Current opinion in biotechnology, 2022 - Elsevier
Highlights•Quantification of biomarkers is necessary for the diagnosis of many
diseases.•Low-cost, point-of-care biomarker quantification remains a challenge.•New …

[HTML][HTML] Cryptococcal meningitis: a review for emergency clinicians

KM Fisher, T Montrief, M Ramzy, A Koyfman… - Internal and emergency …, 2021 - Springer
Abstract Introduction Cryptococcal Meningitis (CM) remains a high-risk clinical condition,
and many patients require emergency department (ED) management for complications and …

[图书][B] Updated recommendations on service delivery for the treatment and care of people living with HIV

World Health Organization - 2021 - books.google.com
These guidelines provide new and updated recommendations and good practice statements
in the following areas: starting ART, including initiating treatment outside the clinic and …

Cryptococcal antigenemia in advanced human immunodeficiency virus disease: pathophysiology, epidemiology, and clinical implications

RM Wake, SF Molloy, JN Jarvis… - Clinical Infectious …, 2023 - academic.oup.com
Cryptococcal antigen (CrAg) is detectable in blood prior to the onset of symptomatic
cryptococcal meningitis (CM), a leading cause of death among people with advanced …

[HTML][HTML] Diagnosis and management of central nervous system cryptococcal infections in HIV-infected adults

C Skipper, M Abassi, DR Boulware - Journal of Fungi, 2019 - mdpi.com
Cryptococcal meningitis persists as a significant source of morbidity and mortality in persons
with HIV/AIDS, particularly in sub-Saharan Africa. Despite increasing access to …

[HTML][HTML] Emerging concepts in HIV-associated cryptococcal meningitis

DS Lawrence, T Boyer-Chammard… - Current opinion in …, 2019 - journals.lww.com
Emerging concepts in HIV-associated cryptococcal meningitis : Current Opinion in Infectious
Diseases Emerging concepts in HIV-associated cryptococcal meningitis : Current Opinion in …

Cryptococcal-related mortality despite fluconazole preemptive treatment in a cryptococcal antigen screen-and-treat program

RM Wake, NP Govender, T Omar, C Nel… - Clinical Infectious …, 2020 - academic.oup.com
Abstract Background Cryptococcal antigen (CrAg) screening and treatment with preemptive
fluconazole reduces the incidence of clinically evident cryptococcal meningitis in individuals …

[HTML][HTML] Field evaluation of validity and feasibility of Pan-Lassa rapid diagnostic test for Lassa fever in Abakaliki, Nigeria: a prospective diagnostic accuracy study

J Elsinga, T Sunyoto, L di Stefano… - The Lancet Infectious …, 2024 - thelancet.com
Background Lassa fever is a viral haemorrhagic fever with few options for diagnosis and
treatment; it is also under-researched with knowledge gaps on its epidemiology. A point-of …