Kidney transplantation is a critical treatment option for end-stage kidney disease patients,
offering improved quality of life and increased survival rates. However, the complexities of …

The identification of the first human polyomavirus BK (BKV) has been over half century, The
previous epidemiological and phylogenetic studies suggest that BKV prevailed and co …

Immunosuppressant drugs (ISDs) are routinely used in clinical practice to maintain organ
transplant survival. However, these drugs are characterized by a restricted therapeutic …

Background Existing guidelines recommend a triple immunosuppressive regimen with
calcineurin inhibitors, antimetabolites, and corticosteroids for postoperative …

For several, also vital medications, such as immunosuppressants in solid organ and
hematopoietic stem cell transplantation, therapeutic drug monitoring (TDM) remains the only …

The purpose of this systematic review and meta-analysis was to compare the risk of non-
melanoma skin cancer (NMSC) and melanoma development in renal transplant recipients …

Nearly every fifth adult in the United States and many older adults worldwide are affected by
chronic kidney disease (CKD), which can progress to kidney failure requiring invasive …

Tacrolimus (TAC) and mycophenolic acid (MPA) provide maintenance immunosuppression
and is dosed empirically in elderly kidney transplant recipients (KTRs) resulting in health …

Background: Tacrolimus (TAC) and mycophenolic acid (MPA) are commonly used
immunosuppressive therapies after renal transplant. Our objective was to quantify TAC and …

Background and Objectives: Endobiogeny is a global systems approach to human biology
based on the concept that the endocrine system manages the metabolism. Biology of …