Currently available delivery systems for genetic drugs have limited utility for systemic
applications. Cationic liposome/plasmid DNA or oligonucleotide complexes are rapidly …

The adsorption of large unilamellar vesicles composed of various combinations of
phosphatidylcholine, phosphatidylethanolamine (PE), monomethyl PE, and dimethyl PE (PE …

Calcific aortic valve disease (CAVD) is the most prevalent valvular heart disease in the
Western population, claiming 17000 deaths per year in the United States and affecting 25 …

We demonstrate a systematic and rational approach to create a library of natural and
modified, dialkylated amino acids based upon arginine for development of an efficient small …

The formation of supported lipid bilayers (SLBs) on glass from giant unilamellar vesicles
(GUVs) was studied using fluorescence microscopy. We show that GUV rupture occurs by at …

To investigate the mechanism of interaction of gramicidin S-like antimicrobial peptides with
biological membranes, a series of five decameric cyclic cationic β-sheet-β-turn peptides with …

Membrane fusion constitutes a pivotal process in eukaryotic cell physiology. Both
specialized proteins and membrane lipids play key roles in fusion. Here, our current …

Membrane fusion is considered relevant in countless scientific areas and biotechnological
processes, ranging from vital life events to biomedicine, pharmaceuticals, and materials …

The peptide sequence B18, derived from the membrane-associated sea urchin sperm
protein bindin, triggers fusion between lipid vesicles. It exhibits many similarities to viral …

Membrane fusion is an important biological process that is observed in a wide variety of intra
and intercellular events. In this review, work done in the last few years on the molecular …