Glucose is the long-established, obligatory fuel for brain that fulfills many critical functions,
including ATP production, oxidative stress management, and synthesis of neurotransmitters …

The mammalian brain depends upon glucose as its main source of energy, and tight
regulation of glucose metabolism is critical for brain physiology. Consistent with its critical …

Abstract Resveratrol (3, 4', 5-trihydroxystilbene; C 14 H 12 O 3) is a polyphenolic phytoalexin
found in grapes, berries, peanuts, and wines. Resveratrol has been viewed as an …

In this review, we focus on lifestyle changes, especially dietary habits, that are at the basis of
chronic systemic low grade inflammation, insulin resistance and Western diseases. Our …

The brain contains a fairly low amount of glycogen, mostly located in astrocytes, a fact that
has prompted the suggestion that glycogen does not have a significant physiological role in …

In statistics and machine learning, model accuracy is traded off with complexity, which can
be viewed as the amount of information extracted from the data. Here, we discuss how …

Local blood flow is modulated in response to changing patterns of neuronal activity, a
process termed neurovascular coupling. It has been proposed that the central cellular …

Glutamate‐stimulated aerobic glycolysis in astrocytes coupled with lactate shuttling to
neurons where it can be oxidized was proposed as a mechanism to couple excitatory …

Aerobic glycolysis occurs during brain activation and is characterized by preferential up‐
regulation of glucose utilization compared with oxygen consumption even though oxygen …

When the brain is in a pathological state, the content of lipid droplets (LDs), the lipid storage
organelles, is increased, particularly in glial cells, but rarely in neurons. The biology and …