Cancer is one of the most common causes of disease-related deaths worldwide. Despite the
discovery of many chemotherapeutic drugs that inhibit uncontrolled cell division processes …

High-performance bioceramics are required for preventing failure and prolonging the life-
time of bone grafting scaffolds and osseous implants. The proper identification and …

The coumarin (benzopyran-2-one, or chromen-2-one) ring system, present in natural
products (such as the anticoagulant warfarin) that display interesting pharmacological …

Bis-coumarins have caused great interests in the recent years. These compounds exhibit
diverse biological activities which are ascribed to their ability to exert noncovalent …

We report on the synthesis of 4-hydroxycoumarin dimers 1–15 bearing an aryl substituent on
the central linker and fused benzopyranocoumarin derivatives 16–20 and on their in vitro …

Complexes of copper (II) with hesperetin, naringenin, and apigenin of general composition
[CuL 2 (H 2 O) 2]⋅ nH 2 O (1–3) have been synthesized and characterized by elemental …

Molecular hybridization represents a new approach in drug discovery in which specific
chromophores are strategically combined to create novel drugs with enhanced therapeutic …

A new series of diverse isoxazoles and triazoles linked 6-hydroxycoumarin (1) were
synthesized using click chemistry approach. All the derivatives were subjected to 3-(4, 5 …

Osthole, an ingredient of Traditional Chinese Medicine (TCM) from natural product Cnidium
monnieri (L.) Cusson, was used as a lead compound for structural modification. A series of …

African geranium (Pelargonium sidoides DC., Geraniaceae) is a herbaceous perennial plant
with well-known medicinal properties. In the present study, the effect of elicitation by methyl …