The emergence and progression of cancers is accompanied by a dysregulation of
transcriptional programs. The three-dimensional (3D) organization of the human genome …

The CCCTC-binding factor (CTCF) binds tens of thousands of enhancers and promoters on
mammalian chromosomes by means of its 11 tandem zinc finger (ZF) DNA-binding domain …

Both obesity and cancer are complex medical conditions that are considered public health
problems. The influence of obesity on the predisposition to develop various types of cancer …

Butyrate is produced in the rumen from microbial fermentation and is related to several
functions, including cell differentiation and proliferation. Butyrate supplementation in calves …

Skin aging is a complex process involving intricate genetic and environmental factors. In this
study, we performed a comprehensive analysis of the transcriptional regulatory landscape of …

Background: Although previous studies have proposed leptin plays an important role in
energy metabolism as well as in immune response, the effects of leptin-related genes on …

The weaning transition in calves is characterized by major structural changes such as an
increase in the rumen capacity and surface area due to diet changes. Studies evaluating …

Chromatin remodeling is a critical step in the DNA damage response, and the ATP-
dependent chromatin remodelers are a group of epigenetic regulators that alter nucleosome …

To better understand how Insm1, Neurod1 and Pax6 contribute to the formation and function
of pancreatic endocrine cells I performed comparative immunohistochemical, transcriptomic …