Pancreatic cancer is a genetic disease, and the recurrent genetic alterations characteristic of
pancreatic cancer indicate the cellular processes that are targeted for malignant …

Pancreatic cancer is one of the solid tumors with the worst prognosis. Five-year survival rate
is less than 10%. Surgical resection is the only potentially curative treatment, but the tumor is …

Pancreatic ductal adenocarcinoma (PDAC), the most deadly solid malignancy, is typically
detected late and at an inoperable stage. Early or incidental detection is associated with …

The current pathological and molecular classification of pancreatic ductal adenocarcinoma
(PDAC) provides limited guidance for treatment options, especially for immunotherapy …

Metastasis has long been understood to lead to the overwhelming majority of cancer-related
deaths. However, our understanding of the metastatic process, and thus our ability to …

Despite the substantial impact of post-translational modifications on programmed cell death
1 ligand 1 (PD-L1), its importance in therapeutic resistance in pancreatic cancer remains …

Cancer-related fatigue (CRF) affects therapeutic compliance and clinical outcomes including
recurrence and mortality. This study aimed to comprehensively and comparatively assess …

BACKGROUND Pancreatic cancer, as the one of most fatal malignancies, remains a critical
issue in the global burden of disease. AIM To estimate trends in pancreatic cancer incidence …

Transcription factors (TFs) are indispensable for the modulation of various signaling
pathways associated with normal cell homeostasis and disease conditions. Among cancer …

Pseudogenes may play important roles in cancer. Here, we explore the mechanism and
function of a pseudogene WTAPP1 in the progress of pancreatic ductal adenocarcinoma …