Pathophysiology and potential future therapeutic targets using preclinical models of COVID-19
Severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) gains entry into the lung
epithelial cells by binding to the surface protein angiotensin-converting enzyme 2. Severe …
epithelial cells by binding to the surface protein angiotensin-converting enzyme 2. Severe …
Genetics of hypertensive syndrome
A Martinez-Aguayo, C Fardella - Hormone Research in Paediatrics, 2009 - karger.com
The knowledge of the genetic bases of hypertension has improved over the last decade; this
area of research has high priority due to the high incidence of hypertension and its impact …
area of research has high priority due to the high incidence of hypertension and its impact …
Preeclampsia in North Indian women: the contribution of genetic polymorphisms
S Aggarwal, N Dimri, I Tandon… - Journal of Obstetrics and …, 2011 - Wiley Online Library
Aim: To find association of angiotensin‐converting enzyme (ACE) insertion/deletion (I/D),
angiotensinogen (AGT) T704C, methylenetetrahydrofolate reductase (MTHFR) C677T and …
angiotensinogen (AGT) T704C, methylenetetrahydrofolate reductase (MTHFR) C677T and …
The effect of liraglutide and sitagliptin on oxidative stress in persons with type 2 diabetes
S Sivalingam, EL Larsen, DH van Raalte… - Scientific reports, 2021 - nature.com
Glucagon-like peptide 1 receptor agonists have shown cardioprotective effects which have
been suggested to be mediated through inhibition of oxidative stress. We investigated the …
been suggested to be mediated through inhibition of oxidative stress. We investigated the …
Genetics meets epigenetics: Genetic variants that modulate noncoding RNA in cardiovascular diseases
After the recent description of the human genome by the ENCODE and the FANTOM
consortia, major attention has been addressed to the so-called “genomic noise”, which …
consortia, major attention has been addressed to the so-called “genomic noise”, which …
Tetra-ARMS-PCR assay development for genotyping of AGT rs699 T/C polymorphism, its comparison with PCR-RFLP and application in a case-control association …
M Hussain, HN Khan, S Abbas, A Ali… - … nucleotides & nucleic …, 2023 - Taylor & Francis
Genetic variations in the AGT gene play a significant role in controlling the plasma
concentration of angiotensinogen (precursor protein of bioactive octapeptide angiotensin II) …
concentration of angiotensinogen (precursor protein of bioactive octapeptide angiotensin II) …
Structural and functional alterations of nitric oxide synthase 3 due to missense variants associate with high-altitude pulmonary edema through dynamic study
H Kanipakam, K Sharma, T Thinlas… - Journal of …, 2021 - Taylor & Francis
The human endothelial nitric oxide synthase (NOS3) is 28 Kbp at 7q36. 1 and encodes
protein comprising of 1280 amino acids. Being a major source of nitric oxide, the enzyme is …
protein comprising of 1280 amino acids. Being a major source of nitric oxide, the enzyme is …
Candidate gene polymorphisms of renin angiotensin system and essential hypertension in a South Indian Tamilian population
P Ramu, G Umamaheswaran… - … journal of human …, 2011 - Taylor & Francis
Genetic variants of renin angiotensin system (RAS) gene play a significant role in the
pathogenesis of essential hypertension and cardiovascular diseases. In the present study …
pathogenesis of essential hypertension and cardiovascular diseases. In the present study …
Haplotype-based association of ACE I/D, AT1R 1166A> C, and AGT M235T polymorphisms in renin–angiotensin–aldosterone system genes in Korean women with …
OBJECTIVES: The objective of this study was to determine whether or not the angiotensin-
converting enzyme insertion/deletion (ACE I/D), angiotensin II type 1 receptor (AT1R), and …
converting enzyme insertion/deletion (ACE I/D), angiotensin II type 1 receptor (AT1R), and …
The genes polymorphism of angiotensinogen (AGT) M235T and AGT T174M in patients with essential hypertension: A meta-analysis
Background Elevated level of angiotensinogen (AGT), a major precursor in the hypertension
pathogenesis, is governed by the single nucleotide polymorphisms (SNPs) of AGT M235T …
pathogenesis, is governed by the single nucleotide polymorphisms (SNPs) of AGT M235T …