Angiogenesis is defined as the formation of new blood vessels from preexisting vessels and
has been characterized as an essential process for tumor cell proliferation and viability. This …

The vascular endothelial growth factor (VEGF)/vascular endothelial growth factor receptor
(VEGFR) axis is indispensable in the process of angiogenesis and has been implicated as a …

The regulation of vascular endothelial growth factor A (VEGF) is critical to
neovascularization in numerous tissues under physiological and pathological conditions …

Preeclampsia is a pregnancy-specific disorder characterized by hypertension and excess
protein excretion in the urine. It is an important cause of maternal and fetal morbidity and …

Background Pulmonary hypertension (PH) is a severe, progressive disease. Although 5 PH
subgroups are recognized, reports on survival have focused mainly on pulmonary arterial …

The vascular endothelial growth factor receptor-1 (VEGFR-1) is a tyrosine kinase receptor
for VEGF-A, VEGF-B, and placental growth factor (PlGF) ligands that is expressed in …

Blood travels throughout the body in an extensive network of vessels–arteries, veins and
capillaries. This vascular network is not static, but instead dynamically remodels in response …

Preeclampsia is a pregnancy-induced hypertensive disorder characterized by proteinuria
and widespread maternal endothelial dysfunction. It remains one of the most common …

The recent launch onto the market of five VEGFR inhibitors indicates the therapeutic value of
these agents and the importance of the research in the field of angiogenesis inhibitors for …

One of the main differences among platelet-rich plasma (PRP) products is the inclusion of
leukocytes that may affect the biological efficacy of these autologous preparations. The …