Tissue-engineered esophagus via bioreactor cultivation for circumferential esophageal reconstruction

IG Kim, Y Wu, SA Park, H Cho, JJ Choi… - … Engineering Part A, 2019 - liebertpub.com
The use of biomaterials for circumferential esophageal repair is technically challenging in a
rat model, and an optimal scaffold implantation technique with nutritional support is …

Experimental investigation of esophageal reconstruction with electrospun polyurethane nanofiber and 3D printing polycaprolactone scaffolds using a rat model

H Park, IG Kim, Y Wu, H Cho, JW Shin, SA Park… - Head & …, 2021 - Wiley Online Library
Background We evaluated the outcome of esophageal reconstructions using tissue‐
engineered scaffolds. Method Partial esophageal defects were reconstructed with the …

Three-dimensional printed design of antibiotic-releasing esophageal patches for antimicrobial activity prevention

SD Kim, IG Kim, HN Tran, H Cho… - … Engineering Part A, 2021 - liebertpub.com
Pharyngoesophageal defects can cause exposure to various bacterial flora and severe
inflammation. We fabricated a biodegradable polycaprolactone (PCL) patch composed of …

[HTML][HTML] Assessment of esophageal reconstruction via bioreactor cultivation of a synthetic scaffold in a canine model

IG Kim, Y Wu, SA Park, JS Choi… - Clinical and …, 2023 - synapse.koreamed.org
Objectives Using tissue-engineered materials for esophageal reconstruction is a technically
challenging task in animals that requires bioreactor training to enhance cellular reactivity …

Perfusion decellularization of porcine esophagus: Study of two processing factors affecting the folded mucosal structure of the esophageal scaffold

S Sitthisang, MF Leong… - Journal of Biomedical …, 2021 - Wiley Online Library
Acellular scaffolds from decellularized donor organs are showing promising clinical results
in tissue and organ repair and regeneration. A successful decellularization process is …

Development of mesenchymal stem cell encoded with myogenic gene for treating radiation-induced muscle fibrosis

IG Kim, SY Eom, H Cho, Y Kim, S Hwang… - Stem Cells and …, 2024 - liebertpub.com
Radiation therapy (RT) is a typical treatment for head and neck cancers. However,
prolonged irradiation of the esophagus can cause esophageal fibrosis due to increased …

Reconstruction of a partial esophageal defect using tunica vaginalis and buccal mucosa autograft: an experimental study in mongrel dogs

MA Hashem, E Metwally, YK Mahmoud… - Journal of Veterinary …, 2023 - jstage.jst.go.jp
In veterinary clinics, esophageal reconstruction is essential in many clinical situations. In this
study, two autografts, the tunica vaginalis (TV) and the buccal mucosa (BM), were proposed …

Esophageal defect repair by artificial scaffolds: a systematic review of experimental studies and proportional meta-analysis

D Schizas, M Frountzas, E Sgouromallis… - Diseases of the …, 2021 - academic.oup.com
Background The traditional technique of gastrointestinal reconstruction of the esophagus
after esophagectomy presents plenty of complications. Hence, tissue engineering has been …

[HTML][HTML] 壳聚糖管状支架联合肌瓣原位重建颈部整段食管的可行性研究

陈刚, 刘波颖, 康其伟, 温晓, 曾俍铭, 王晓阳 - 中国医科大学学报, 2020 - html.rhhz.net
目的探讨壳聚糖管状支架联合肌瓣原位重建颈部食管整段缺损的可行性. 方法将大耳白兔(30 只)
制成3~ 5 mm 食管整段缺损动物模型, 缺如处置入壳聚糖管状支架, 外覆颈部肌肉组织瓣包裹 …

Alternative non-oral nutrition in a rat model: a novel modified gastrostomy technique

IG Kim, H Cho, JJ Choi, JW Shin, EJ Chung - Experimental Animals, 2022 - jstage.jst.go.jp
The gastrostomy technique is essential for esophageal reconstruction using a scaffold. To
date, there are no established methods to supply nutrients through a gastrostomy tube in …